Evidence map›Paper›PMID 23791426›Full record

ArticleInternational journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases2013

Maternal risk factors for HIV infection in infants in northeastern Brazil.

Lígia M D de Lemos, Joseph Lippi, George W Rutherford, Gabriella S Duarte, Nágyla G R Martins, Victor S Santos, Ricardo Q Gurgel

Abstract read
In one paragraph

Article in International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Article
  6. Article
  7. Article
  8. Review
  9. Article
  10. Article
  11. Viral Sepsis in Children.Frontiers in pediatrics · 2018
    Review
  12. Article
  13. HIV Prevalence among Pregnant Women in Brazil: A National Survey.Revista brasileira de ginecologia e obstetricia : revista da Federacao Brasileira das Sociedades de Ginecologia e Obstetricia · 2016
    Article
  14. Article
  15. Cascade of access to interventions to prevent HIV mother to child transmission in the metropolitan area of Rio de Janeiro, Brazil.The Brazilian journal of infectious diseases : an official publication of the Brazilian Society of Infectious Diseases
    Article
  16. Article
  17. Effectiveness of the prevention of mother-to-child HIV transmission in Bahia, Brazil.The Brazilian journal of infectious diseases : an official publication of the Brazilian Society of Infectious Diseases
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Lígia M D de LemosDepartment of Nursing, Federal University of Sergipe, Aracaju, Sergipe, Brazil. Electronic address: ligiadolce@gmail.com.
Joseph Lippi
George W Rutherford
Gabriella S Duarte
Nágyla G R Martins
Victor S Santos
Ricardo Q Gurgel

Funding

Fogarty International Clinical Research Scholars Support Center @ Vanderbilt-AAMCR24TW007988 · FIC · VANDERBILT UNIVERSITY · PI VERMUND, STEN H. · 2007 to 2011
$27.6M
University of California, Berkeley (UCB)/University of *D43TW000003 · FIC · UNIVERSITY OF CALIFORNIA BERKELEY · PI REINGOLD, ARTHUR L · 1988 to 2013
$16.7M
ICOHRTA Visiting Scientists ProgramD43TW005799 · FIC · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI RUTHERFORD, GEORGE WILLIAMS · 2001 to 2011
$2.5M
FIC NIH HHS D43 TW000003FIC NIH HHS D43TW000003FIC NIH HHS D43 TW005799FIC NIH HHS R24 TW007988FIC NIH HHS R24TW007988
6 · The paper itself

Abstract

introductionWhile the rate of vertically transmitted HIV infection has fallen in most regions of Brazil, there have been no similar decreases in northern and northeastern Brazil.

objectiveThe objective of this study was to evaluate the risk factors associated with vertical transmission in the state of Sergipe in northeastern Brazil.

methodsThis was a retrospective cohort study. We recorded clinic and registry data for all HIV-infected pregnant women and exposed children diagnosed in Sergipe from 1990 to 2011.

resultsWe identified 538 deliveries and 561 HIV-exposed infants (23 sets of twins). One hundred one (18.9%) infants were HIV-infected. In the multivariate analysis, infant antiretroviral prophylaxis was a significant protective factor (adjusted odds ratio (aOR) 0.07, 95% confidence interval (CI) 0.01-0.41, p=0.003). Breastfeeding was marginally associated with an increased odds of perinatal transmission (aOR 4.52, 95% CI 0.78-26.17, p = 0.092). The attributable risk percentage for breastfeeding over the study period was 91.0%. Transmission decreased from 91 per 100 live births before 1997 to 2 per 100 in 2011 following the adoption of the prevention protocol.

conclusionTransmission declined over the study period. The screening of pregnant women and timely initiation of prophylaxis and therapy are issues that require further attention.

Indexed as

AdultAnti-HIV AgentsBirth WeightBrazilBreast FeedingFemaleHIV InfectionsHumansInfantInfant, NewbornInfectious Disease Transmission, VerticalMaleMaternal-Fetal ExchangeMiddle AgedMultivariate AnalysisPregnancyAnti-HIV AgentsBreastfeedingHIVPregnancyVertical infectious disease transmission

Identifiers

PMID23791426
PMCPMC5463571

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.