Evidence map›Paper›PMID 23791189›Full record

ArticleNeuron2013

In search of the ever-elusive positive endozepine.

Stephen C Harward, James O McNamara

Open access · bronzeAbstract readComment
In one paragraph

Article in Neuron, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.3field-weighted citation impact, top 45% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Stephen C HarwardDepartment of Neurobiology, Duke University Medical Center, Durham, NC 27710, USA.
James O McNamara
Duke University · US

Funding

MEDICAL SCIENTIST TRAINING PROGRAMT32GM007171 · NIGMS · DUKE UNIVERSITY · PI KONTOS, CHRISTOPHER D · 1985 to 2021
$31.2M
Neurotrophins and EpileptogenesisR01NS056217 · NINDS · DUKE UNIVERSITY · PI MCNAMARA, JAMES O. · 2006 to 2023
$6.7M
TrkB receptor activationF31NS078847 · NINDS · DUKE UNIVERSITY · PI HARWARD, STEPHEN CANNADA · 2012 to 2014
$95k
NIGMS NIH HHS T32 GM007171NINDS NIH HHS F31 NS078847NINDS NIH HHS R01 NS056217
6 · The paper itself

Abstract

In this issue of Neuron, Christian et al. (2013) provide functional evidence for positive endozepines (positive allosteric modulators of GABAARs) within the thalamic reticular nucleus. These molecules are encoded by the Dbi gene and modulate thalamocortical oscillations.

Indexed as

AnimalsDiazepam Binding InhibitorFemaleInhibitory Postsynaptic PotentialsMaleReceptors, GABA-AThalamusDiazepam Binding InhibitorReceptors, GABA-A

Identifiers

PMID23791189
PMCPMC3732046
OpenAlexW2127478258

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.