Trial reportDrug and alcohol dependence2013
Inattention, impulsive action, and subjective response to D-amphetamine.
Trial report in Drug and alcohol dependence, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
23 citing papers in PubMed, 32 citations in OpenAlex.
- The relationship between novelty-seeking traits and behavior: Establishing construct validity for the human Behavioral Pattern Monitor.Psychiatry research · 2022Trial
- Neural correlates of inhibitory control are associated with stimulant-like effects of alcohol.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2021Trial
- Poor inhibitory control is associated with greater stimulation and less sedation following alcohol.Psychopharmacology · 2020Trial
- Amphetamine improves mouse and human attention in the 5-choice continuous performance test.Neuropharmacology · 2018Trial
- Drug liking and wanting, not impulsive action or reflection is increased by 4-fluoroamphetamine.Psychopharmacology · 2018Trial
- Acute effects of lisdexamfetamine and D-amphetamine on social cognition and cognitive performance in a placebo-controlled study in healthy subjects.Psychopharmacology · 2018Trial
- Amphetamine Modestly Improves Conners' Continuous Performance Test Performance in Healthy Adults.Journal of the International Neuropsychological Society : JINS · 2018Trial
- Sweet taste liking is associated with subjective response to amphetamine in women but not men.Psychopharmacology · 2017Trial
- Associations Between Behavioral and Neural Correlates of Inhibitory Control and Amphetamine Reward Sensitivity.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2017Trial
- Amphetamine increases activity but not exploration in humans and mice.Psychopharmacology · 2016Trial
- Nucleus accumbens functional connectivity changes underlying alcohol expectancies in bipolar disorder and prospective alcohol outcomes: a within-subject randomized placebo-controlled alcohol administration fMRI study.Frontiers in neuroscience · 2025Article
- Behavioral phenotypes revealed during reversal learning are linked with novel genetic loci in diversity outbred mice.Addiction neuroscience · 2022Article
- A Role for Serotonin in Modulating Opposing Drive and Brake Circuits of Impulsivity.Frontiers in behavioral neuroscience · 2022Review
- DThe Journal of neuroscience : the official journal of the Society for Neuroscience · 2021Article
- Disentangling the effects of cannabis and cigarette smoking on impulsivity.Journal of psychopharmacology (Oxford, England) · 2020Article
- Methamphetamine acutely alters frontostriatal resting state functional connectivity in healthy young adults.Addiction biology · 2020Article
- Distinct acute effects of LSD, MDMA, and D-amphetamine in healthy subjects.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2020Article
- Subjective responses to amphetamine in young adults with previous mood elevation experiences.Psychopharmacology · 2019Article
- Safety Profile and Neurocognitive Function Following Acute 4-Fluoroamphetamine (4-FA) Administration in Humans.Frontiers in pharmacology · 2018Article
- Premature responding is associated with approach to a food cue in male and female heterogeneous stock rats.Psychopharmacology · 2016Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
Abstract
backgroundBoth impulsivity and sensitivity to the rewarding effects of drugs have long been considered risk factors for drug abuse. There is some preclinical evidence to suggest that the two are related; however, there is little information about how specific behavioral components of impulsivity are related to the acute euphorigenic effects of drugs in humans. The aim of the current study was to examine the degree to which both inattention and impulsive action predicted subjective response to amphetamine.
methodsHealthy adults (n=165) performed the behavioral tasks and rated their subjective response to amphetamine (0, 5, 10, and 20 mg). Inattention was assessed as attention lapses on a simple reaction time task, and impulsive action was measured by stop RT on the stop task. Subjective response to amphetamine was assessed with the Drug Effects Questionnaire (DEQ) and the Profile of Mood States (POMS).
resultsHierarchical linear regression analyses showed significant negative associations between attention lapses and subjective response to amphetamine on DEQ measures. By contrast, stop RT was positively associated with responses on both DEQ and POMS measures. Additionally, a dose-response relationship was observed, such that the strength of these associations increased with higher doses of amphetamine.
conclusionsThese findings suggest that inattention is associated with less subjective response to amphetamine. By contrast, the heightened sensitivity to stimulant drug reward observed in individuals high in impulsive action suggests that this might be one mechanism contributing to increased risk for stimulant drug abuse in these individuals.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.