ArticleBiophysical journal2013
Thermal mechanisms of millimeter wave stimulation of excitable cells.
Article in Biophysical journal, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
16 citing papers in PubMed.
- Wireless neuromodulation at submillimeter precision via a microwave split-ring resonator.Science advances · 2024Article
- Advances in Millimeter-Wave Treatment and Its Biological Effects Development.International journal of molecular sciences · 2024Review
- Thermal safety considerations for implantable micro-coil design.Journal of neural engineering · 2023Article
- Optocapacitance: physical basis and its application.Biophysical reviews · 2022Review
- [Study on the temperature characteristics of fast capacitance in patch clamp experiments].Sheng wu yi xue gong cheng xue za zhi = Journal of biomedical engineering = Shengwu yixue gongchengxue zazhi · 2021Article
- 5G Wireless Communication and Health Effects-A Pragmatic Review Based on Available Studies Regarding 6 to 100 GHz.International journal of environmental research and public health · 2019Review
- Multiplexing Focused Ultrasound Stimulation with Fluorescence Microscopy.Journal of visualized experiments : JoVE · 2019Article
- AThe Journal of general physiology · 2018Article
- Brilliant Stimulation, One Cell at a Time.Biophysical journal · 2018Article
- Effect of acute millimeter wave exposure on dopamine metabolism of NGF-treated PC12 cells.Journal of radiation research · 2017Article
- Ryanodine and IPNeurophotonics · 2017Article
- Optical magnetic detection of single-neuron action potentials using quantum defects in diamond.Proceedings of the National Academy of Sciences of the United States of America · 2016Article
- Axonal model for temperature stimulation.Journal of computational neuroscience · 2016Article
- Chloride Anions Regulate Kinetics but Not Voltage-Sensor Qmax of the Solute Carrier SLC26a5.Biophysical journal · 2016Article
- Real-time imaging of electrical signals with an infrared FDA-approved dye.Biophysical journal · 2014Article
- Physical principles for scalable neural recording.Frontiers in computational neuroscience · 2013Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
Abstract
Interactions between millimeter waves (MMWs) and biological systems have received increasing attention due to the growing use of MMW radiation in technologies ranging from experimental medical devices to telecommunications and airport security. Studies have shown that MMW exposure alters cellular function, especially in neurons and muscles. However, the biophysical mechanisms underlying such effects are still poorly understood. Due to the high aqueous absorbance of MMW, thermal mechanisms are likely. However, nonthermal mechanisms based on resonance effects have also been postulated. We studied MMW stimulation in a simplified preparation comprising Xenopus laevis oocytes expressing proteins that underlie membrane excitability. Using electrophysiological recordings simultaneously with 60 GHz stimulation, we observed changes in the kinetics and activity levels of voltage-gated potassium and sodium channels and a sodium-potassium pump that are consistent with a thermal mechanism. Furthermore, we showed that MMW stimulation significantly increased the action potential firing rate in oocytes coexpressing voltage-gated sodium and potassium channels, as predicted by thermal terms in the Hodgkin-Huxley model of neurons. Our results suggest that MMW stimulation produces significant thermally mediated effects on excitable cells via basic thermodynamic mechanisms that must be taken into account in the study and use of MMW radiation in biological systems.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.