Evidence map›Paper›PMID 23790368›Full record

ArticleBiophysical journal2013

Elasticity and biochemistry of growth relate replication rate to cell length and cross-link density in rod-shaped bacteria.

Akeisha M T Belgrave, Charles W Wolgemuth

Open access · bronzeAbstract read
In one paragraph

Article in Biophysical journal, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.2field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Recombinant Peptide Production SoftensInternational journal of molecular sciences · 2023
    Article
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 1 country.

Akeisha M T BelgraveUniversity of Connecticut Health Center, Department of Cell Biology and Center for Cell Analysis and Modeling, Farmington, Connecticut, USA.
Charles W Wolgemuth
UConn Health · USUniversity of Arizona · US

Funding

Elastic Model of Spirochete Morphology and MotilityR01GM072004 · NIGMS · UNIVERSITY OF CONNECTICUT SCH OF MED/DNT · PI WOLGEMUTH, CHARLES W · 2004 to 2013
$2.2M
NIGMS NIH HHS R01 GM072004
6 · The paper itself

Abstract

In rod-shaped bacteria, cell morphology is correlated with the replication rate. For a given species, cells that replicate faster are longer and have less cross-linked cell walls. Here, we propose a simple mechanochemical model that explains the dependence of cell length and cross-linking on the replication rate. Our model shows good agreement with existing experimental data and provides further evidence that cell wall synthesis is mediated by multienzyme complexes; however, our results suggest that these synthesis complexes only mediate glycan insertion and cross-link severing, whereas recross-linking is performed independently.

Indexed as

Cell Growth ProcessesDNA ReplicationModels, BiologicalBacteriaBacterial Physiological PhenomenaCell WallElasticity

Identifiers

PMID23790368
PMCPMC3686348
OpenAlexW2137273441

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.