Evidence map›Paper›PMID 23790353›Full record

SynthesisLancet (London, England)2013

Socioeconomic development as an intervention against malaria: a systematic review and meta-analysis.

Lucy S Tusting, Barbara Willey, Henry Lucas, John Thompson, Hmooda T Kafy, Richard Smith, Steve W Lindsay

Abstract readMeta-AnalysisSystematic Review
PubMed Publisher
In one paragraph

Synthesis in Lancet (London, England), 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 137 papers, 11 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
137citing papers in PubMed, 11 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

137 citing papers in PubMed, 11 syntheses or guidelines pooled it.

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  5. Prevalence of malaria relapse: systematic review with meta-analysis.Revista latino-americana de enfermagem · 2019
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  10. A systematic review and meta-analysis of dengue risk with temperature change.International journal of environmental research and public health · 2014
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77 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors.

Lucy S TustingLondon School of Hygiene & Tropical Medicine, London, UK.
Barbara Willey
Henry Lucas
John Thompson
Hmooda T Kafy
Richard Smith
Steve W Lindsay

Funding

Medical Research Council G0700837
6 · The paper itself

Abstract

backgroundFuture progress in tackling malaria mortality will probably be hampered by the development of resistance to drugs and insecticides and by the contraction of aid budgets. Historically, control was often achieved without malaria-specific interventions. Our aim was to assess whether socioeconomic development can contribute to malaria control.

methodsWe did a systematic review and meta-analysis to assess whether the risk of malaria in children aged 0-15 years is associated with socioeconomic status. We searched Medline, Web of Science, Embase, the Cochrane Database of Systematic Reviews, the Campbell Library, the Centre for Reviews and Dissemination, Health Systems Evidence, and the Evidence for Policy and Practice Information and Co-ordinating Centre evidence library for studies published in English between Jan 1, 1980, and July 12, 2011, that measured socioeconomic status and parasitologically confirmed malaria or clinical malaria in children. Unadjusted and adjusted effect estimates were combined in fixed-effects and random-effects meta-analyses, with a subgroup analysis for different measures of socioeconomic status. We used funnel plots and Egger's linear regression to test for publication bias.

findingsOf 4696 studies reviewed, 20 met the criteria for inclusion in the qualitative analysis, and 15 of these reported the necessary data for inclusion in the meta-analysis. The odds of malaria infection were higher in the poorest children than in the least poor children (unadjusted odds ratio [OR] 1·66, 95% CI 1·35-2·05, p<0·001, I(2)=68%; adjusted OR 2·06, 1·42-2·97, p<0·001, I(2)=63%), an effect that was consistent across subgroups.

interpretationAlthough we would not recommend discontinuation of existing malaria control efforts, we believe that increased investment in interventions to support socioeconomic development is warranted, since such interventions could prove highly effective and sustainable against malaria in the long term.

fundingUK Department for International Development.

Indexed as

Economic DevelopmentAdolescentAdultAfricaAgedChildChild, PreschoolCost of IllnessGross Domestic ProductHumansInfantMalaria, FalciparumMiddle AgedPovertySocioeconomic FactorsYoung Adult

Identifiers

PMID23790353

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.