Evidence map›Paper›PMID 23790311›Full record

ReviewCurrent opinion in chemical biology2013

Recent trends in analytical and structural glycobiology.

Milos V Novotny, William R Alley

Abstract readReview
In one paragraph

Review in Current opinion in chemical biology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Milos V NovotnyDepartment of Chemistry, Indiana University, Bloomington, IN 47405, United States. Electronic address: novotny@indiana.edu.
William R Alley

Funding

ULTRASENSITIVE METHODS FOR GLYCOCONJUGATE ANALYSISR01GM024349 · NIGMS · TRUSTEES OF INDIANA UNIVERSITY · PI NOVOTNY, MILOS · 1985 to 2014
$2.9M
NIGMS NIH HHS R01 GM024349NIGMS NIH HHS R01-GM024349
6 · The paper itself

Abstract

The great complexity of glycosylated biomolecules necessitates a set of powerful analytical methodologies to reveal functionally important structural features. Mass spectrometry (MS), with its different ionization techniques, mass analyzers, and detection strategies, has become the most important analytical method in glycomic and glycoproteomic investigations. In combination with MS, microscale separations (based on capillary chromatography and electrophoresis) and carbohydrate microchemistry, we feature here conceptually important applications of the recent years. This review focuses on methodological advances pertaining to disease biomarker research, immunology, developmental biology, and measurements of importance to biopharmaceuticals. High-sensitivity determinations and sample enrichment/preconcentration are particularly emphasized in glycomic and glycoproteomic profiling.

Indexed as

AnimalsGlycomicsGlycopeptidesGlycoproteinsHumansMass SpectrometryPolysaccharidesProteomicsGlycopeptidesGlycoproteinsPolysaccharides

Identifiers

PMID23790311
PMCPMC3823762

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.