ArticleSocial neuroscience2013
Afraid to help: social anxiety partially mediates the association between 5-HTTLPR triallelic genotype and prosocial behavior.
Article in Social neuroscience, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
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Who cites it
15 citing papers in PubMed, 47 citations in OpenAlex.
- Personality and Situational Determinants of Sustained Helping Towards Ukrainian War Refugees in 2022.Psychology research and behavior management · 2024Article
- Encouraging a Peer in Need: The Impacts of Social Anxiety and Peer Familiarity.Social development (Oxford, England) · 2023Article
- The Interaction between Serotonin Transporter Allelic Variation and Maternal Care Modulates Instagram Sociability in a Sample of Singaporean Users.International journal of environmental research and public health · 2022Article
- Prosocialness in young males with substance and behavioral addictions.Journal of behavioral addictions · 2021Article
- Molecular and neurocircuitry mechanisms of social avoidance.Cellular and molecular life sciences : CMLS · 2021Review
- Empathy as a Concept from Bench to Bedside: A Translational Challenge.Noro psikiyatri arsivi · 2020Review
- The nature and nurture of social development: The role of 5-HTTLPR and gene-parenting interactions.Journal of family psychology : JFP : journal of the Division of Family Psychology of the American Psychological Association (Division 43) · 2019Article
- Serotonin Receptor 1A Variation Is Associated with Anxiety and Agonistic Behavior in Chimpanzees.Molecular biology and evolution · 2019Article
- Article
- Shyness Weakens the Agreeableness-Prosociality Association via Social Self-Efficacy: A Moderated-Mediation Study of Chinese Undergraduates.Frontiers in psychology · 2019Article
- From Empathy to Apathy: The Bystander Effect Revisited.Current directions in psychological science · 2018Article
- Anxiolytic Treatment Impairs Helping Behavior in Rats.Frontiers in psychology · 2016Article
- Top-Down Control of Serotonin Systems by the Prefrontal Cortex: A Path toward Restored Socioemotional Function in Depression.ACS chemical neuroscience · 2015Review
- Unselfish genes? The quest to uncover genomic influences on prosocial behavior.Social neuroscience · 2013Article
- With a little help from our friends: how the brain processes empathy.Cerebrum : the Dana forum on brain scienceArticle
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3 authors at 2 institutions in 1 country.
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No grant is acknowledged in the PubMed record.
Abstract
There is growing evidence that the serotonin system influences prosocial behavior. We examined whether anxiety mediated the association between variation in the serotonin transporter gene regulatory region (5-HTTLPR) and prosocial behavior. We collected self-reported tendencies to avoid certain situations and history of helping others using standard instruments and buccal cells for standard 5-HTTLPR genotyping from 398 undergraduate students. Triallelic 5-HTTLPR genotype was significantly associated with prosocial behavior and the effect was partially mediated by social anxiety, such that those carrying the S' allele reported higher levels of social avoidance and lower rates of helping others. These results are consistent with accounts of the role of serotonin on anxiety and prosocial behavior and suggest that targeted efforts to reduce social anxiety in S' allele carriers may enhance prosocial behavior.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.