ArticleEcology and evolution2013
Embryonic lethality leads to hybrid male inviability in hybrids between Drosophila melanogaster and D. santomea.
Article in Ecology and evolution, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
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Who cites it
9 citing papers in PubMed.
- System drift and speciation.Evolution; international journal of organic evolution · 2022Article
- The microbiome impacts host hybridization and speciation.PLoS biology · 2021Article
- A morphological trait involved in reproductive isolation between Drosophila sister species is sensitive to temperature.Ecology and evolution · 2021Article
- Biophysics and population size constrains speciation in an evolutionary model of developmental system drift.PLoS computational biology · 2019Article
- The Effect of Temperature onG3 (Bethesda, Md.) · 2017Article
- Establishment of F1 hybrid mortality in real time.BMC evolutionary biology · 2017Article
- Simple Biophysical Model Predicts Faster Accumulation of Hybrid Incompatibilities in Small Populations Under Stabilizing Selection.Genetics · 2015Article
- Fine mapping of dominant X-linked incompatibility alleles in Drosophila hybrids.PLoS genetics · 2014Article
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2 authors.
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Abstract
The study of the morphological defects unique to interspecific hybrids can reveal which developmental pathways have diverged between species. Drosophila melanogaster and D. santomea diverged more than 10 million years ago, and when crossed produce sterile adult females. Adult hybrid males are absent from all interspecific crosses. We aimed to determine the fate of these hybrid males. To do so, we tracked the development of hybrid females and males using classic genetic markers and techniques. We found that hybrid males die predominantly as embryos with severe segment-specification defects while a large proportion of hybrid females embryos hatch and survive to adulthood. In particular, we show that most male embryos show a characteristic abdominal ablation phenotype, not observed in either parental species. This suggests that sex-specific embryonic developmental defects eliminate hybrid males in this interspecific cross. The study of the developmental abnormalities that occur in hybrids can lead to the understanding of cryptic molecular divergence between species sharing a conserved body plan.
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