Evidence map›Paper›PMID 23788695›Full record

Trial reportPsychosomatic medicine

Effect of meditation on endothelial function in Black Americans with metabolic syndrome: a randomized trial.

Viola Vaccarino, Kofi A Kondwani, Mary E Kelley, Nancy V Murrah, Linda Boyd, Yusuf Ahmed, Yuan X Meng, Gary H Gibbons, W Craig Hooper, Christine De Staercke and 1 more

Open access · greenAbstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Psychosomatic medicine. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 4 pooled it
0.2field-weighted citation impact, top 43% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 4 syntheses or guidelines pooled it, 12 citations in OpenAlex.

  1. Pooled it
  2. Effectiveness of Mantra-Based Meditation on Mental Health: A Systematic Review and Meta-Analysis.International journal of environmental research and public health · 2022
    Pooled it
  3. Systematic Review for the Medical Applications of Meditation in Randomized Controlled Trials.International journal of environmental research and public health · 2022
    Pooled it
  4. Guideline
  5. Review
  6. Observational
  7. Review
  8. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 1 country.

Viola VaccarinoDepartment of Epidemiology, Rollins School of Public Health, Emory University, Atlanta, GA 30322, USA. viola.vaccarino@emory.edu
Kofi A Kondwani
Mary E Kelley
Nancy V Murrah
Linda Boyd
Yusuf Ahmed
Yuan X Meng
Gary H Gibbons
W Craig Hooper
Christine De Staercke
Arshed A Quyyumi
Emory University · USMorehouse School of Medicine · US

Funding

Atlanta Clinical and Translational Science Institute (ACTSI) RenewalUL1TR000454 · NCATS · EMORY UNIVERSITY · PI STEPHENS, DAVID S · 2012 to 2016
$25.8M
X LINKED NYSTAGMUS SYNDROME WITH FEATURES OF ALBINISMM01RR000039 · NCRR · EMORY UNIVERSITY · PI VACCARINO, VIOLA · 1985 to 2007
$21.3M
WARCEFP20RR011104 · NCRR · MOREHOUSE SCHOOL OF MEDICINE · PI HIGGINBOTHAM, EVE J. · 1995 to 2009
$14.5M
Social Exposures and Genetics of Cardiovascular DiseaseZIAHG200393 · NHGRI · NATIONAL HUMAN GENOME RESEARCH INSTITUTE · PI GIBBONS, GARY · 2014 to 2019
$13.1M
Metabolomics of subclinical and clinical cardiovascular diseaseP20HL113451 · NHLBI · EMORY UNIVERSITY · PI JONES, DEAN PAUL · 2012 to 2016
$4.3M
The Emory-Morehouse Partnership to Reduce CV DisparitiesU01HL079156 · NHLBI · EMORY UNIVERSITY · PI QUYYUMI, ARSHED A · 2004 to 2008
$3.1M
Stress-reduction in African Americans with metabolic synU01HL079214 · NHLBI · MOREHOUSE SCHOOL OF MEDICINE · PI LAPU-BULA, · 2004 to 2008
$2.9M
Mind-Body Interactions in Cardiovascular DiseaseK24HL077506 · NHLBI · EMORY UNIVERSITY · PI VACCARINO, VIOLA · 2004 to 2013
$1.5M
NCATS NIH HHS UL1 TR000454NCRR NIH HHS 5P20RR11104NCRR NIH HHS M01 RR000039NCRR NIH HHS M01-RR00039NCRR NIH HHS P20 RR011104NHLBI NIH HHS K24 HL077506NHLBI NIH HHS K24HL077506NHLBI NIH HHS P20 HL113451NHLBI NIH HHS U01 HL079156NHLBI NIH HHS U01 HL079214NHLBI NIH HHS U01 HL79214
6 · The paper itself

Abstract

objectivesPsychological stress may play a role in metabolic syndrome. A consequence of metabolic syndrome is endothelial dysfunction, which is also influenced by psychological stress. We sought to compare the effect of consciously resting meditation (CRM), a sound based meditation, with a control intervention of health education (HE) on endothelial function in the setting of metabolic syndrome.

methodsSixty-eight black Americans with metabolic syndrome risk factors (age, 30-65 years) were randomized to either CRM (n = 33) or HE (n = 35); interventions were matched for frequency and duration of sessions and lasted 12 months. Endothelial function was assessed by brachial artery flow-mediated dilation at baseline and at 6 and 12 months. Arterial elasticity, metabolic risk factors, and psychosocial and behavioral variables were secondary end points.

resultsAlthough flow-mediated dilation improved in the CRM group for 12 months, this increase was not significantly higher than that in the HE group (p = .51 for the interaction between group and time). Non-endothelium-dependent dilation and arterial elasticity did not change in either group. Most metabolic syndrome risk factors showed beneficial trends in the CRM group only. A risk factor score counting the number of metabolic syndrome components decreased in the CRM group only (p = .049 for the interaction between treatment group and time).

conclusionsAmong black Americans with metabolic syndrome risk factors, CRM, did not improve endothelial function significantly more than a control intervention of HE. CRM resulted in favorable trends in metabolic syndrome risk factors, which were examined as secondary outcomes.

Indexed as

Black or African AmericanAdultAgedBrachial ArteryElasticityEndothelium, VascularFemaleHealth EducationHumansMaleMeditationMetabolic SyndromeMiddle AgedPulse Wave AnalysisRisk FactorsVasodilationEndotheliummetabolic syndromeobesitystress

Identifiers

PMID23788695
PMCPMC3774317
OpenAlexW2036117623

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.