ArticleAJNR. American journal of neuroradiology2013
Stroke-like migraine attacks after radiation therapy (SMART) syndrome is not always completely reversible: a case series.
Article in AJNR. American journal of neuroradiology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 51 papers.
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Who cites it
51 citing papers in PubMed, 120 citations in OpenAlex.
- Post-therapy imaging of adult brain tumours: patterns, pitfalls, and practical framework.Insights into imaging · 2026Article
- Neurological Puzzles After Radiotherapy: Mysterious Clues of Smart Syndrome, Two Case Reports.Journal of clinical ultrasound : JCU · 2026Article
- Headache as a Sentinel Signal After Cranial Radiotherapy: A Symptom-Driven Approach to Pathophysiology and Management.Neurology international · 2026Review
- Risk factors and long-term outcomes in smart syndrome: a multicenter study.Journal of neuro-oncology · 2026Article
- Epilepsy in Patients with Cerebral Radiation Necrosis: A Scoping Review.Medicina (Kaunas, Lithuania) · 2026Article
- Stroke-Like Migraine Attacks After Radiation Therapy (SMART) Syndrome: A Case Report and Review of a Rare Delayed Complication of Cranial Irradiation.Clinical case reports · 2026Article
- Case Report: longitudinal imaging in a patient with SMART syndrome after cranial radiotherapy.Frontiers in oncology · 2026Article
- Article
- Stroke-like migraine attack after radiation therapy (SMART) syndrome in a pediatric patient with a ventriculoperitoneal shunt: illustrative case.Journal of neurosurgery. Case lessons · 2025Article
- Chronic Neurological Complications of Brain Tumors and Brain Tumor Treatments.Current neurology and neuroscience reports · 2025Review
- Positron Emission Tomography and Magnetic Resonance Imaging Findings in the Diagnosis of Stroke-Like Migraine Attacks after Radiation Therapy Syndrome: A Case Report.Advances in radiation oncology · 2024Article
- Article
- Mitigating Radiotoxicity in the Central Nervous System: Role of Proton Therapy.Current treatment options in oncology · 2023Review
- SMART syndrome: a case report.Acta neurologica Belgica · 2023Article
- Comprehensive Update and Review of Clinical and Imaging Features of SMART Syndrome.AJNR. American journal of neuroradiology · 2023Review
- Arterial spin labeling clinical applications for brain tumors and tumor treatment complications: A comprehensive case-based review.The neuroradiology journal · 2023Review
- [Stroke-like migraine attacks after radiation therapy (SMART) syndrome: a rare sequelae after cerebral radiotherapy].Der Nervenarzt · 2023Article
- SMART Syndrome: Case Report and Review of the Literature.Journal of the Belgian Society of Radiology · 2023Article
- Case Report: Stroke-like migraine attacks after radiation therapy syndrome: a rare complication 26 years after cranial radiotherapy.Frontiers in oncology · 2023Article
- SMART syndrome: two cases highlighting a complex and rare complication of brain irradiation.BMJ case reports · 2022Article
Corrections and comments
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Authors and funding
7 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
We retrospectively reviewed clinical and imaging findings in 11 patients with stroke-like migraine attacks after radiation therapy (SMART) syndrome to better understand this disorder previously thought to be reversible. Six men and 5 women had complex bouts of neurologic impairment beginning, on average, 20 years after cerebral irradiation. All had characteristic, unilateral gyriform enhancement on MR imaging that developed within 2-7 days and typically resolved in 2-5 weeks. Unlike prior reports, 45% had incomplete neurologic recovery manifesting as dysphasia, cognitive impairment, or hemiparesis. The remaining 55% recovered completely over an average of 2 months. Three of 11 patients developed cortical laminar necrosis. Brain biopsies in 4 of 11 did not demonstrate a specific pathologic substrate. These additional 11 patients contribute to the understanding of variability in stroke-like migraine attacks after radiation therapy syndrome, which often but not uniformly manifests with headaches and seizures, demonstrates a typical evolution of imaging findings, and may result in permanent neurologic and imaging sequelae.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.