Evidence map›Paper›PMID 23788510›Full record

Trial reportObesity (Silver Spring, Md.)2014

An 8-month randomized controlled exercise trial alters brain activation during cognitive tasks in overweight children.

Cynthia E Krafft, Nicolette F Schwarz, Lingxi Chi, Abby L Weinberger, David J Schaeffer, Jordan E Pierce, Amanda L Rodrigue, Nathan E Yanasak, Patricia H Miller, Phillip D Tomporowski and 2 more

Registry-linked trialAbstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Obesity (Silver Spring, Md.), 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02227095 (Exercise & Overweight Children's Cognition), which is not on this map. Cited by 97 papers, 21 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
97citing papers in PubMed, 21 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02227095 nacompletednot on this map

Exercise & Overweight Children's Cognition

TypeinterventionalSponsorAugusta UniversityRan2008 to 2014Enrolled175ConditionsOverweight and ObesityArmsExercise, After-school program
3 · Its place in the literature

Who cites it

97 citing papers in PubMed, 21 syntheses or guidelines pooled it.

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37 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Cynthia E KrafftPsychology Department, University of Georgia, Athens, Georgia, USA.
Nicolette F Schwarz
Lingxi Chi
Abby L Weinberger
David J Schaeffer
Jordan E Pierce
Amanda L Rodrigue
Nathan E Yanasak
Patricia H Miller
Phillip D Tomporowski
Catherine L Davis
Jennifer E McDowell

Funding

Exercise & Overweight Children's CognitionR01HL087923 · NHLBI · AUGUSTA UNIVERSITY · PI DAVIS, CATHERINE LUCY, MCDOWELL, JENNIFER E · 2008 to 2012
$5.2M
NHLBI NIH HHS R01 HL087923NHLBI NIH HHS R01 HL87923
6 · The paper itself

Abstract

objectiveChildren who are less fit reportedly have lower performance on tests of cognitive control and differences in brain function. This study examined the effect of an exercise intervention on brain function during two cognitive control tasks in overweight children. DESIGN AND

methodsParticipants included 43 unfit, overweight (BMI ≥ 85th percentile) children 8- to 11-years old (91% Black), who were randomly divided into either an aerobic exercise (n = 24) or attention control group (n = 19). Each group was offered a separate instructor-led after-school program every school day for 8 months. Before and after the program, all children performed two cognitive control tasks during functional magnetic resonance imaging (fMRI): antisaccade and flanker.

resultsCompared to the control group, the exercise group decreased activation in several regions supporting antisaccade performance, including precentral gyrus and posterior parietal cortex, and increased activation in several regions supporting flanker performance, including anterior cingulate and superior frontal gyrus.

conclusionsExercise may differentially impact these two task conditions, or the paradigms in which cognitive control tasks were presented may be sensitive to distinct types of brain activation that show different effects of exercise. In sum, exercise appears to alter efficiency or flexible modulation of neural circuitry supporting cognitive control in overweight children.

Indexed as

Exercise TherapyOverweightAttentionBrainChildCognitionFemaleHumansMagnetic Resonance ImagingMaleSedentary Behavior

Identifiers

PMID23788510
PMCPMC4077546

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.