Modeling predictors, moderators and mediators of treatment outcome and resistance in depression.

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

Who cites it

18 citing papers in PubMed, 1 synthesis or guideline pooled it.

1. Genetic endophenotypes for insomnia of major depressive disorder and treatment-induced insomnia.Journal of neural transmission (Vienna, Austria : 1996) · 2019
   Pooled it
2. Prefrontal networks dynamically related to recovery from major depressive disorder: a longitudinal pharmacological fMRI study.Translational psychiatry · 2019
   Trial
3. Platelet-Derived Growth Factor as an Antidepressant Treatment Selection Biomarker: Higher Levels Selectively Predict Better Outcomes with Bupropion-SSRI Combination.The international journal of neuropsychopharmacology · 2017
   Trial
4. Exercise is an effective treatment for positive valence symptoms in major depression.Journal of affective disorders · 2017
   Trial
5. Affect Following First Exercise Session as a Predictor of Treatment Response in Depression.The Journal of clinical psychiatry · 2016
   Trial
6. Establishing moderators and biosignatures of antidepressant response in clinical care (EMBARC): Rationale and design.Journal of psychiatric research · 2016
   Trial
7. Neurocognitive effects of ketamine and association with antidepressant response in individuals with treatment-resistant depression: a randomized controlled trial.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2015
   Trial
8. Neurocognitive predictors of antidepressant clinical response.Journal of affective disorders · 2014
   Trial
9. Biomarkers in Psychiatric Drug Development: From Precision Medicine to Novel Therapeutics.Advances in neurobiology · 2023
   Article
10. The Entorhinal Cortex and Adult Neurogenesis in Major Depression.International journal of molecular sciences · 2021
    Review
11. Serotonergic receptor gene polymorphism and response to selective serotonin reuptake inhibitors in ethnic Malay patients with first episode of major depressive disorder.The pharmacogenomics journal · 2021
    Review
12. Neural Circuitry-Neurogenesis Coupling Model of Depression.International journal of molecular sciences · 2021
    Review
13. Cerebral Blood Perfusion Predicts Response to Sertraline versus Placebo for Major Depressive Disorder in the EMBARC Trial.EClinicalMedicine · 2019
    Article
14. Can an Integrated Science Approach to Precision Medicine Research Improve Lithium Treatment in Bipolar Disorders?Frontiers in psychiatry · 2018
    Review
15. Reevaluating the Efficacy and Predictability of Antidepressant Treatments: A Symptom Clustering Approach.JAMA psychiatry · 2017
    Article
16. Right patient, right treatment, right time: biosignatures and precision medicine in depression.World psychiatry : official journal of the World Psychiatric Association (WPA) · 2016
    Article
17. Prediction of treatment outcomes in psychiatry--where do we stand ?Dialogues in clinical neuroscience · 2014
    Review
18. Adiponectin Moderates Antidepressant Treatment Outcome in the Combining Medications to Enhance Depression Outcomes Randomized Clinical Trial.Personalized medicine in psychiatry
    Article

Corrections and comments

• Comment on
  A clinical risk stratification tool for predicting treatment resistance in major depressive disorder.2013

Authors and funding

1 author.

Funding

No grant is acknowledged in the PubMed record.

Abstract

PubMed holds no abstract for this paper.

Indexed as