Evidence map›Paper›PMID 23786629›Full record

ArticleJournal of agricultural and food chemistry2013

Stable binding of alternative protein-enriched food matrices with concentrated cranberry bioflavonoids for functional food applications.

Mary H Grace, Ivette Guzman, Diana E Roopchand, Kristin Moskal, Diana M Cheng, Natasha Pogrebnyak, Ilya Raskin, Amy Howell, Mary Ann Lila

Open access · greenAbstract read
In one paragraph

Article in Journal of agricultural and food chemistry, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
4.5field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 65 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. The Role of Hemp (Foods (Basel, Switzerland) · 2023
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Mary H GracePlants for Human Health Institute, Food, Bioprocessing, and Nutrition Sciences Department, North Carolina State University, Kannapolis, North Carolina 28081, United States.
Ivette Guzman
Diana E Roopchand
Kristin Moskal
Diana M Cheng
Natasha Pogrebnyak
Ilya Raskin
Amy Howell
Mary Ann Lila
Rutgers, The State University of New Jersey · USNorth Carolina State University · USCranberry Institute · US

Funding

Training in Botanical Approaches to Combat Metabolic SyndromeT32AT004094 · NCCIH · LSU PENNINGTON BIOMEDICAL RESEARCH CTR · PI BRANTLEY, PHILLIP J, STEPHENS, JACQUELINE M · 2009 to 2024
$5.7M
Concentrating anti-UTI phytochemicals from cranberry in a functional food matrixR43DK092104 · NIDDK · NUTRASORB, LLC · PI MAY , WILLIAM · 2011 to 2012
$327k
NCCIH NIH HHS T32 AT004094NIDDK NIH HHS 1R43DK092104-01A1NIDDK NIH HHS R43 DK092104
6 · The paper itself

Abstract

Defatted soy flour (DSF), soy protein isolate (SPI), hemp protein isolate (HPI), medium-roast peanut flour (MPF), and pea protein isolate (PPI) stably bind and concentrate cranberry (CB) polyphenols, creating protein/polyphenol-enriched matrices. Proanthocyanidins (PAC) in the enriched matrices ranged from 20.75 mg/g (CB-HPI) to 10.68 mg/g (CB-SPI). Anthocyanins (ANC) ranged from 3.19 mg/g (CB-DSF) to 1.68 mg/g (CB-SPI), whereas total phenolics (TP) ranged from 37.61 mg/g (CB-HPI) to 21.29 mg/g (CB-SPI). LC-MS indicated that the enriched matrices contained all identifiable ANC, PAC, and flavonols present in CB juice. Complexation with SPI stabilized and preserved the integrity of the CB polyphenolic components for at least 15 weeks at 37 °C. PAC isolated from enriched matrices demonstrated comparable antiadhesion bioactivity to PAC isolated directly from CB juice (MIC 0.4-0.16 mg/mL), indicating their potential utility for maintenance of urinary tract health. Approximately 1.0 g of polyphenol-enriched matrix delivered the same amount of PAC available in 1 cup (300 mL) of commercial CB juice cocktail, which has been shown clinically to be the prophylactic dose for reducing recurring urinary tract infections. CB-SPI inhibited Gram-positive and Gram-negative bacterial growth. Nutritional and sensory analyses indicated that the targeted CB-matrix combinations have high potential for incorporation in functional food formulations.

Indexed as

Food, FortifiedFunctional FoodAnthocyaninsAnti-Bacterial AgentsArachisBeveragesCannabisDietary ProteinsFlavonoidsFruitPlant ProteinsPolyphenolsProanthocyanidinsSoybean ProteinsUrinary Tract InfectionsVaccinium macrocarponAnthocyaninsAnti-Bacterial AgentsDietary ProteinsFlavonoidsPlant ProteinsPolyphenolsProanthocyanidinsSoybean Proteins

Identifiers

PMID23786629
PMCPMC3769697
OpenAlexW1986765256

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.