Evidence map›Paper›PMID 2378651›Full record

ArticleMolecular and cellular biology1990

Correction of the N-terminal sequences of the human plastin isoforms by using anchored polymerase chain reaction: identification of a potential calcium-binding domain.

C S Lin, R H Aebersold, J Leavitt

Abstract readComparative Study
In one paragraph

Article in Molecular and cellular biology, 1990. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
1.6field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 39 citations in OpenAlex.

  1. Article
  2. Article
  3. Human PDE5A gene encodes three PDE5 isoforms from two alternate promoters.International journal of impotence research · 2002
    Article
  4. Article
  5. Article
  6. Interpreting cDNA sequences: some insights from studies on translation.Mammalian genome : official journal of the International Mammalian Genome Society · 1996
    Review
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

C S LinCalifornia Institute for Medical Research, San Jose 95128.
R H Aebersold
J Leavitt

Funding

ROLES OF MICROFILAMENT PROTEINS IN NEOPLASIA/METASTASISR01CA034763 · NCI · PALO ALTO MEDICAL FOUNDATION RES INST · PI LEAVITT, JOHN C · 1986 to 1993
–
ROLE OF METASCHEMATIN PROTEINS IN NEOPLASIAR01CA049423 · NCI · PALO ALTO MEDICAL FOUNDATION RES INST · PI LIN, CHINGSHWUN · 1989 to 1991
–
NCI NIH HHS CA34763NCI NIH HHS CA49423
6 · The paper itself

Abstract

Plastins are a family of at least three cytoplasmic protein isoforms that are expressed differentially between cells of the hematopoietic lineages and cells of solid tissues. Expression of the L-plastin isoform appears to be restricted to replicating blood cells, and the two T-plastin isoforms appear to be restricted to replicating cells of solid tissues. However, L-plastin is induced in many human solid tumor-derived cells. We used the anchored polymerase chain reaction technique to amplify and clone the missing 5' ends of plastin mRNAs. We found that both plastin isoforms contain a potential calcium binding site near the N terminus.

Indexed as

PhosphoproteinsAmino Acid SequenceBase SequenceCalciumCalmodulinDNAGenetic VariationHumansMembrane GlycoproteinsMicrofilament ProteinsMolecular Sequence DataOligonucleotide ProbesPolymerase Chain ReactionProtein BindingProteinsRNA, MessengerCalciumCalmodulinDNAMembrane GlycoproteinsMicrofilament ProteinsOligonucleotide ProbesPhosphoproteinsplastinProteinsRNA, Messenger

Identifiers

PMID2378651
PMCPMC362293
OpenAlexW2291596525

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.