ReviewJournal of biomedical science2013
Animal models of diabetic retinopathy: doors to investigate pathogenesis and potential therapeutics.
Review in Journal of biomedical science, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
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Who cites it
21 citing papers in PubMed.
- Tree shrew model of early diabetic retinopathy reveals microvascular dysfunction and identifies phosphoserine aminotransferase 1 as a novel therapeutic target.Animal models and experimental medicine · 2026Article
- Contributions and future potential of animal models for geroscience research on sensory systems.GeroScience · 2025Review
- Diabetic retinopathy: a comprehensive update on in vivo, in vitro and ex vivo experimental models.BMC ophthalmology · 2023Review
- Jin-Gui-Shen-Qi Wan ameliorates diabetic retinopathy by inhibiting apoptosis of retinal ganglion cells through the Akt/HIF-1α pathway.Chinese medicine · 2023Article
- ThePharmaceuticals (Basel, Switzerland) · 2022Article
- Diabetic neovascularization defects in the retina are improved by genistein supplementation in the ovariectomized rat.Inflammopharmacology · 2021Article
- Animal models of diabetic retinopathy.Annals of translational medicine · 2021Review
- Non-invasive multimodal imaging of Diabetic Retinopathy: A survey on treatment methods and Nanotheranostics.Nanotheranostics · 2021Article
- Preclinical Efficacy and Safety of VEGF-Grab, a Novel Anti-VEGF Drug, and Its Comparison to Aflibercept.Investigative ophthalmology & visual science · 2020Article
- Proceedings of the 2019 National Toxicology Program Satellite Symposium.Toxicologic pathology · 2019Article
- Extract of the Blood Circulation-Promoting Recipe-84 Can Protect Rat Retinas by Inhibiting the β-Catenin Signaling Pathway.International journal of molecular sciences · 2018Article
- The Novel Pathogenesis of Retinopathy Mediated by Multiple RTK Signals is Uncovered in Newly Developed Mouse Model.EBioMedicine · 2018Article
- Small GTPase ARF6 controls VEGFR2 trafficking and signaling in diabetic retinopathy.The Journal of clinical investigation · 2017Article
- OCT angiography and visible-light OCT in diabetic retinopathy.Vision research · 2017Review
- Animal Models of Diabetic Retinopathy.Current diabetes reports · 2017Review
- Article
- Increased Retinal Oxygen Metabolism Precedes Microvascular Alterations in Type 1 Diabetic Mice.Investigative ophthalmology & visual science · 2017Article
- Involvement of Autophagic Pathway in the Progression of Retinal Degeneration in a Mouse Model of Diabetes.Frontiers in cellular neuroscience · 2016Article
- Characterization of cells from patient-derived fibrovascular membranes in proliferative diabetic retinopathy.Molecular vision · 2015Article
- Natural product inhibitors of ocular angiogenesis.Experimental eye research · 2014Review
Corrections and comments
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Effective and validated animal models are valuable to investigate the pathogenesis and potential therapeutics for human diseases. There is much concern for diabetic retinopathy (DR) in that it affects substantial number of working population all around the world, resulting in visual deterioration and social deprivation. In this review, we discuss animal models of DR based on different species of animals from zebrafish to monkeys and prerequisites for animal models. Despite criticisms on imprudent use of laboratory animals, we hope that animal models of DR will be appropriately utilized to deepen our understanding on the pathogenesis of DR and to support our struggle to find novel therapeutics against catastrophic visual loss from DR.
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