ArticleJournal of cancer survivorship : research and practice2013
Health-related quality of life in survivors of childhood cancer: the role of chronic health problems.
Article in Journal of cancer survivorship : research and practice, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03297034 (Swiss Childhood Cancer Survivor Study), which is not on this map. Cited by 41 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Swiss Childhood Cancer Survivor Study (SCCSS)
Who cites it
41 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Severe fatigue after treatment for childhood cancer.The Cochrane database of systematic reviews · 2020Pooled it
- Psychosocial Follow-Up in Survivorship as a Standard of Care in Pediatric Oncology.Pediatric blood & cancer · 2015Pooled it
- Effect of a 1-year physical activity intervention on cardiovascular health in long-term childhood cancer survivors-a randomised controlled trial (SURfit).British journal of cancer · 2023Trial
- Yield of Urinalysis Screening in Pediatric Cancer Survivors.Pediatric blood & cancer · 2016Trial
- The impact of clinically relevant health conditions on psychosocial outcomes in survivors of childhood cancer: results of the DCCSS-LATER study.Journal of cancer survivorship : research and practice · 2025Article
- Neurocognitive and Emotional Outcomes in Childhood Cancer: A Developmental Perspective.Current oncology (Toronto, Ont.) · 2025Review
- A prospective cohort study on the trajectory of health-related quality of life in adult childhood cancer survivors attending a follow-up care program.Scientific reports · 2025Article
- Auditory complications among childhood cancer survivors and health-related quality of life: a PanCareLIFE study.Journal of cancer survivorship : research and practice · 2025Article
- Positive and negative survivor-specific psychosocial consequences of childhood cancer: the DCCSS-LATER 2 psycho-oncology study.Journal of cancer survivorship : research and practice · 2024Article
- Article
- Incidence and prevalence of musculoskeletal health conditions in survivors of childhood and adolescent cancers: A report from the Swiss childhood cancer survivor study.Cancer medicine · 2024Article
- Quality of life after pediatric cancer: comparison of long-term childhood cancer survivors' quality of life with a representative general population sample and associations with physical health and risk indicators.Health and quality of life outcomes · 2023Article
- Self-reported outcomes on oral health and oral health-related quality of life in long-term childhood cancer survivors-A DCCSS-LATER 2 Study.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2023Article
- Health-related quality of life in adults after pediatric kidney failure in Switzerland.Pediatric nephrology (Berlin, Germany) · 2023Article
- The mediating role of appraisal on health-related quality of life in adolescent and young adult cancer survivors.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2023Article
- Brothers and sisters of childhood acute leukemia survivors: Their long-term quality of life and its determinants.Cancer medicine · 2023Article
- Longitudinal analysis of health care costs in patients with childhood onset inherited retinal dystrophies compared to healthy controls.BMC ophthalmology · 2022Article
- Article
- Article
- Prevalence and risk factors of cancer-related fatigue in childhood cancer survivors: A DCCSS LATER study.Cancer · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionThe influence of specific health problems on health-related quality of life (HRQoL) in childhood cancer survivors is unknown. We compared HRQoL between survivors of childhood cancer and their siblings, determined factors associated with HRQoL, and investigated the influence of chronic health problems on HRQoL.
methodsWithin the Swiss Childhood Cancer Survivor Study, we sent a questionnaire to all survivors (≥16 years) registered in the Swiss Childhood Cancer Registry, who survived >5 years and were diagnosed 1976-2005 aged <16 years. Siblings received similar questionnaires. We assessed HRQoL using Short Form-36 (SF-36). Health problems from a standard questionnaire were classified into overweight, vision impairment, hearing, memory, digestive, musculoskeletal or neurological, and thyroid problems.
resultsThe sample included 1,593 survivors and 695 siblings. Survivors scored significantly lower than siblings in physical function, role limitation, general health, and the Physical Component Summary (PCS). Lower score in PCS was associated with a diagnosis of central nervous system tumor, retinoblastoma or bone tumor, having had surgery, cranio-spinal irradiation, or bone marrow transplantation. Lower score in Mental Component Summary was associated with older age. All health problems decreased HRQoL in all scales. Most affected were survivors reporting memory problems and musculoskeletal or neurological problems. Health problems had the biggest impact on physical functioning, general health, and energy and vitality.
conclusionsIn this study, we showed the negative impact of specific chronic health problems on survivors' HRQoL. IMPLICATIONS FOR CANCER SURVIVORS: Therapeutic preventive measures, risk-targeted follow-up, and interventions might help decrease health problems and, consequently, improve survivors' quality of life.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.