ArticlePlant physiology2013
The HERBIVORE ELICITOR-REGULATED1 gene enhances abscisic acid levels and defenses against herbivores in Nicotiana attenuata plants.
Article in Plant physiology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 37 papers.
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Who cites it
37 citing papers in PubMed, 81 citations in OpenAlex.
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- Fall Armyworm Frass Induce Sorghum Defenses Against Insect Herbivores.Journal of chemical ecology · 2025Article
- Spider mite herbivory induces an ABA-driven stomatal defense.Plant physiology · 2024Article
- Combined miRNA and mRNA sequencing reveals the defensive strategies of resistant YHY15 rice against differentially virulent brown planthoppers.Frontiers in plant science · 2024Article
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- Transcriptome profiling in rice reveals a positive role for OsNCED3 in defense against the brown planthopper, Nilaparvata lugens.BMC genomics · 2022Article
- Transcriptome Analysis Reveals Crosstalk between the Abscisic Acid and Jasmonic Acid Signaling Pathways in Rice-Mediated Defense againstInternational journal of molecular sciences · 2022Article
- Identification and Functional Analysis of lncRNA by CRISPR/Cas9 During the Cotton Response to Sap-Sucking Insect Infestation.Frontiers in plant science · 2022Article
- Mayetiola destructor (Diptera: Cecidmyiidae) host preference and survival on small grains with respect to leaf reflectance and phytohormone concentrations.Scientific reports · 2021Article
- Interspecific interactions within a vector-borne complex are influenced by a co-occurring pathosystem.Scientific reports · 2021Article
- Aphid-Responsive Defense Networks in Hybrid Switchgrass.Frontiers in plant science · 2020Article
- The Clock Gene TOC1 in Shoots, Not Roots, Determines Fitness ofPlant physiology · 2019Article
- Effects of sugarcane aphid herbivory on transcriptional responses of resistant and susceptible sorghum.BMC genomics · 2018Article
- Plant Perception and Short-Term Responses to Phytophagous Insects and Mites.International journal of molecular sciences · 2018Review
- The Active Jasmonate JA-Ile Regulates a Specific Subset of Plant Jasmonate-Mediated Resistance to Herbivores in Nature.Frontiers in plant science · 2018Article
- Argonaute 8 (AGO8) Mediates the Elicitation of Direct Defenses against Herbivory.Plant physiology · 2017Article
- Flower-specific jasmonate signaling regulates constitutive floral defenses in wild tobacco.Proceedings of the National Academy of Sciences of the United States of America · 2017Article
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3 authors at 1 institution in 1 country.
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Abstract
Nicotiana attenuata plants can distinguish the damage caused by herbivore feeding from other types of damage by perceiving herbivore-associated elicitors, such as the fatty acid-amino acid conjugates (FACs) in oral secretions (OS) of Manduca sexta larvae, which are introduced into wounds during feeding. However, the transduction of FAC signals into downstream plant defense responses is still not well established. We identified a novel FAC-regulated protein in N. attenuata (NaHER1; for herbivore elicitor regulated) and show that it is an indispensable part of the OS signal transduction pathway. N. attenuata plants silenced in the expression of NaHER1 by RNA interference (irHER1) were unable to amplify their defenses beyond basal, wound-induced levels in response to OS elicitation. M. sexta larvae performed 2-fold better when reared on irHER1 plants, which released less volatile organic compounds (indirect defense) and had strongly reduced levels of several direct defense metabolites, including trypsin proteinase inhibitors, 17-hydroxygeranyllinallool diterpene glycosides, and caffeoylputrescine, after real and/or simulated herbivore attack. In parallel to impaired jasmonate signaling and metabolism, irHER1 plants were more drought sensitive and showed reduced levels of abscisic acid (ABA) in the leaves, suggesting that silencing of NaHER1 interfered with ABA metabolism. Because treatment of irHER1 plants with ABA results in both the accumulation of significantly more ABA catabolites and the complete restoration of normal wild-type levels of OS-induced defense metabolites, we conclude that NaHER1 acts as a natural suppressor of ABA catabolism after herbivore attack, which, in turn, activates the full defense profile and resistance against herbivores.
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