ArticleTumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine2013
Extension of microRNA expression pattern associated with high-risk neuroblastoma.
Article in Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
13 citing papers in PubMed, 18 citations in OpenAlex.
- The emerging role of miR-362 in cancer: expression and function across different cancer types.Medical oncology (Northwood, London, England) · 2025Review
- Epigenetic Dysregulation inInternational journal of molecular sciences · 2023Review
- Neuroblastoma and the epigenome.Cancer metastasis reviews · 2021Review
- Circ-CUX1 Accelerates the Progression of Neuroblastoma via miR-16-5p/DMRT2 Axis.Neurochemical research · 2020Article
- miR-373 promotes neuroblastoma cell proliferation, migration, and invasion by targeting SRCIN1.OncoTargets and therapy · 2019Article
- Role of MicroRNA-93 I in Pathogenesis of Left Ventricular Remodeling via Targeting Cyclin-D1.Medical science monitor : international medical journal of experimental and clinical research · 2017Article
- A sketch of known and novel MYCN-associated miRNA networks in neuroblastoma.Oncology reports · 2017Article
- A comparison of microRNA expression profiles from splenic hemangiosarcoma, splenic nodular hyperplasia, and normal spleens of dogs.BMC veterinary research · 2016Article
- MicroRNA-93 suppress colorectal cancer development via Wnt/β-catenin pathway downregulating.Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine · 2015Article
- Effects of the Pinggan Qianyang Recipe on MicroRNA Gene Expression in the Aortic Tissue of Spontaneously Hypertensive Rats.Evidence-based complementary and alternative medicine : eCAM · 2015Article
- Significance and therapeutic value of miRNAs in embryonal neural tumors.Molecules (Basel, Switzerland) · 2014Review
- The roles of microRNAs in neuroblastoma.World journal of pediatrics : WJP · 2014Review
- MicroRNA regulation of tumorigenesis, cancer progression and interpatient heterogeneity: towards clinical use.Genome biology · 2014Review
Corrections and comments
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Authors and funding
8 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Clinical behavior of neuroblastoma (NBL) is remarkably heterogeneous, as it ranges from spontaneous regression to aggressive clinical phenotype and death. There is increasing body of evidence demonstrating that microRNAs could be considered the potential biomarkers for clinical applications in NBL. In this report, we focus on molecular characterization of high-risk as well as low-risk and intermediate-risk NBL cases in the context of the microRNA expression profile that is specific for the given risk category of the disease. We investigated a total of 30 NBL patients, out of whom there were 19 patients with low- to intermediate-risk and 11 with high-risk NBLs as defined by the Clinical Oncology Group. We determined the expression profiles of 754 microRNAs (miRNAs), whereas the miRNA expression levels were normalized to RNU44, mean expression levels were calculated, and data were analyzed by use of the microarray biostatistical approaches. We identified the signature of 38 miRNAs differentially expressed between these groups of NBL patients (P < 0.05): 17 miRNAs were upregulated and 21 miRNAs were downregulated in the tumors of high-risk NBL patients. We confirm some of the previous observations and we report several new microRNAs associated with aggressive NBL, both being relevant subjects for further translational validation and functional studies.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.