Evidence map›Paper›PMID 23783997›Full record

ArticleDer Ophthalmologe : Zeitschrift der Deutschen Ophthalmologischen Gesellschaft2013

[Atrophic age-related macular degeneration].

C N von Strachwitz

Abstract readEnglish Abstract
PubMed Publisher
In one paragraph

Article in Der Ophthalmologe : Zeitschrift der Deutschen Ophthalmologischen Gesellschaft, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.5field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 4 citations in OpenAlex.

  1. [Forms of age-related macular degeneration].Der Ophthalmologe : Zeitschrift der Deutschen Ophthalmologischen Gesellschaft · 2015
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author at 1 institution in 1 country.

C N von StrachwitzAugenCentrum Südwest, Hauptstrasse 4, Stuttgart, Germany. strachwitz@augencentrum-suedwest.de
Augencentrum Rosenheim · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Atrophic age-related macular degeneration (AMD) is a degenerative disorder of the central retina that greatly increases with age. This complex disease is mainly based on a genetic background but environmental factors are most likely responsible for modulating the individual course of the disorder. Various mechanisms are thought to underlie this chronic disorder. Besides defective inflammatory control pathways, increased susceptibility to oxidative stress and defective clearing mechanisms of waste products, primary atrophy of photoreceptors and choroidal capillaries may also lead to the typical clinical signs and symptoms of AMD. Therapeutic approaches therefore aim at modulation of the different disease pathways which probably differ from individual to individual. In the future customized therapeutic strategies are expected to be of great value to slow down disease progression or even prevent outbreak of the disorder.

Indexed as

Geographic AtrophyGenetic Predisposition to DiseaseHumans

Identifiers

PMID23783997
OpenAlexW12309924

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.