ArticleOdontology2014
Blood vessels are concentrated within the implant surface concavities: a histologic study in rabbit tibia.
Article in Odontology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
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Who cites it
19 citing papers in PubMed, 43 citations in OpenAlex.
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- Design of a Haversian system-like gradient porous scaffold based on triply periodic minimal surfaces for promoting bone regeneration.Journal of advanced research · 2023Article
- Laser microgrooving and resorbable blast texturing for enhanced surface function of titanium alloy for dental implant applications.Biomedical engineering advances · 2023Article
- Long-Bone-Regeneration Process in a Sheep Animal Model, Using Hydroxyapatite Ceramics Prepared by Tape-Casting Method.Bioengineering (Basel, Switzerland) · 2023Article
- Histological and Biological Response to Different Types of Biomaterials: A Narrative Single Research Center Experience over Three Decades.International journal of environmental research and public health · 2022Review
- Healing Pattern Analysis for Dental Implants Using the Mechano-Regulatory Tissue Differentiation Model.International journal of molecular sciences · 2020Article
- Customizable 3D-Printed (Co-)Cultivation Systems for In Vitro Study of Angiogenesis.Materials (Basel, Switzerland) · 2020Article
- Titanium Implants Coated with a Bifunctional Molecule with Antimicrobic Activity: A Rabbit Study.Materials (Basel, Switzerland) · 2020Article
- Histological and Histomorphometrical Evaluation of a New Implant Macrogeometry. A Sheep Study.International journal of environmental research and public health · 2020Article
- 3-dimensional visualization of implant-tissue interface with the polyethylene glycol associated solvent system tissue clearing method.Cell proliferation · 2019Article
- Biomimetic Surfaces Coated with Covalently Immobilized Collagen Type I: An X-Ray Photoelectron Spectroscopy, Atomic Force Microscopy, Micro-CT and Histomorphometrical Study in Rabbits.International journal of molecular sciences · 2019Article
- Engineering vasculature: Architectural effects on microcapillary-like structure self-assembly.PloS one · 2019Article
- Ultrasonic vs Drill Implant Site Preparation: Post-Operative Pain Measurement Through VAS, Swelling and Crestal Bone Remodeling: A Randomized Clinical Study.Materials (Basel, Switzerland) · 2018Article
- Three-Dimensional Architecture and Mechanical Properties of Bovine Bone Mixed with Autologous Platelet Liquid, Blood, or Physiological Water: An In Vitro Study.International journal of molecular sciences · 2018Article
- The Biological Properties of OGI Surfaces Positively Act on Osteogenic and Angiogenic Commitment of Mesenchymal Stem Cells.Materials (Basel, Switzerland) · 2017Article
- Article
- Bone Response to Two Dental Implants with Different Sandblasted/Acid-Etched Implant Surfaces: A Histological and Histomorphometrical Study in Rabbits.BioMed research international · 2017Article
Corrections and comments
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Authors and funding
7 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Angiogenesis plays a key role in bone formation and maintenance. Bone formation has been reported to initiate in the concavities rather than the convexities in a hydroxyapatite substratum and the implant threads of dental implants. The aim of the present study was to evaluate the number of the blood vessels inside the concavities and around the convexities of the threads of implants in a rabbit tibia model. A total of 32 thread-shaped implants blasted with apatitic calcium phosphate (TCP/HA blend) (Resorbable Blast Texturing, RBT) (Maestro, BioHorizons(®), Birmingham, AL, USA) were inserted in 8 rabbits. Each rabbit received 4 implants, 2 in the right and 2 in left tibia. Implants were retrieved after 1, 2, 4, and 8 weeks and treated to obtain thin ground sections. Statistically significant differences were found in the number of vessels that had formed in the concavities rather than the convexities of the implants after 1 (p = 0.000), and 2 weeks (p = 0.000), whilst no significant differences after 4 (p = 0.546) and 8 weeks (p = 0.275) were detected. The present results supported the hypothesis that blood vessel formation was stimulated by the presence of the concavities, which may provide a suitable environment in which mechanical forces, concentrations and gradients of chemotactic molecules and blood clot retention may all drive vascular and bone cell migration.
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