Evidence map›Paper›PMID 23783553›Full record

ArticleSurgical endoscopy2013

Clinical outcomes of endoscopic and surgical management for postoperative upper gastrointestinal leakage.

Seohyun Lee, Ji Yong Ahn, Hwoon-Yong Jung, Jeong Hoon Lee, Kwi-Sook Choi, Do Hoon Kim, Kee Don Choi, Ho June Song, Gin Hyug Lee, Jin-Ho Kim and 5 more

2 registry-linked trialsAbstract read
PubMed Publisher
In one paragraph

Article in Surgical endoscopy, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
2.4field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03529266 phase2completednot on this mapstarted 2018, after this paper: background citation

Porcine Fibrin Sealant in Preventing Cervical Anastomotic Leakage After Esophagectomy for Esophageal or Junctional Carcinoma: A Phase II,Single Arm,Prospective Study.

TypeinterventionalSponsorSun Yat-sen UniversityRan2018 to 2021Enrolled57ConditionsEsophageal Cancer, Gastroesophageal Junction Cancer, Anastomotic LeakArmsPorcine Fibrin Sealant (PFS), Surgery
NCT03847857 phase3active not recruitingnot on this mapstarted 2019, after this paper: background citation

A Multicenter Prospective Randomized Controlled Study of Porcine Fibrin Sealant in Preventing Cervical Anastomotic Leakage for Esophageal or Junctional Carcinoma. (PLACE030)

TypeinterventionalSponsorSun Yat-sen UniversityRan2019 to 2025Enrolled360ConditionsEsophageal Anastomotic LeakArmsPorcine Fibrin Sealant (PFS), McKeown esophagectomy
3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 44 citations in OpenAlex.

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  14. Endoluminal Vacuum Therapy: How I Do It.Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract · 2019
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  20. Results of endoscopic and surgical fistula treatment in oesophagointestinal anastomosis after gastrectomy.Wideochirurgia i inne techniki maloinwazyjne = Videosurgery and other miniinvasive techniques · 2016
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 3 institutions in 1 country.

Seohyun LeeDepartment of Gastroenterology, Asan Medical Center, Asan Digestive Disease Research Institute, University of Ulsan College of Medicine, No. 388-1 Pungnap-2 dong, Songpa-gu, Seoul, 138-736, Korea, seohyunism@naver.com.
Ji Yong Ahn
Hwoon-Yong Jung
Jeong Hoon Lee
Kwi-Sook Choi
Do Hoon Kim
Kee Don Choi
Ho June Song
Gin Hyug Lee
Jin-Ho Kim
Beom Su Kim
Jeong Hwan Yook
Sung Tae Oh
Byung Sik Kim
Seungbong Han
Asan Medical Center · KRUlsan College · KRUniversity of Ulsan · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe purpose of this study was to evaluate the safety and efficacy of endoscopic therapy, an alternative and less invasive modality for the management of leakage after gastrectomy.

methodsAn electronic database of 35 patients with anastomotic leaks after surgery for stomach cancer that were treated with either an endoscopic procedure or surgery between January 2004 and March 2012 was reviewed. The success rates and safety of both modalities were evaluated.

resultsEndoscopic treatment was performed in 20 patients and surgical treatment in 15 patients. The median time interval between the primary surgery and diagnosis of leakage was 8.0 days (interquartile range, 5.0-14.0 days). Of the 20 patients with endoscopic treatment, technical success was achieved in 19 patients (95 %) with resulting clinical success achieved in all of these 19 patients (100 %). One patient with failed endoscopic management went on to receive surgery. There were no cases of leakage-related deaths after endoscopic treatment. Of the 15 patients with surgical treatment, 5 died due to sepsis, bleeding, or hospital-acquired pneumonia. For diagnosis of leakage, 17 patients from the endoscopy group underwent computed tomography (CT) scanning, which revealed leakages in 3 patients (17.6 %) and occult leakages were subsequently defined at fluoroscopy in all 20 patients. Seven of twelve patients (58.3 %) from the surgical group had leakages diagnosed by CT scan.

conclusionsEndoscopic treatment can be considered a valuable option for the management of postoperative anastomotic leakage with a high degree of technical feasibility and safety, particularly for leakages that are not excessively large.

Indexed as

AgedAnastomosis, SurgicalAnastomotic LeakEndoscopyFemaleFluoroscopyGastrectomyHumansMaleMiddle AgedStomach NeoplasmsTomography, X-Ray ComputedTreatment Outcome

Identifiers

PMID23783553
OpenAlexW2048350161

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.