ArticleProceedings. Biological sciences2013
Sex-linked transcriptional divergence in the hermaphrodite fungus Neurospora tetrasperma.
Article in Proceedings. Biological sciences, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
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Who cites it
17 citing papers in PubMed, 32 citations in OpenAlex.
- Genetic differentiation in the MAT-proximal region is not sufficient for suppressing recombination in Podospora anserina.G3 (Bethesda, Md.) · 2025Article
- Yeast sexes: mating types do not determine the sexes in Metschnikowia species.FEMS yeast research · 2024Article
- The Sordariomycetes: an expanding resource with Big Data for mining in evolutionary genomics and transcriptomics.Frontiers in fungal biology · 2023Review
- Nuclear-specific gene expression in heterokaryons of the filamentous ascomyceteProceedings. Biological sciences · 2022Article
- Mating Systems in True Morels (Microbiology and molecular biology reviews : MMBR · 2021Review
- Recombination suppression and evolutionary strata around mating-type loci in fungi: documenting patterns and understanding evolutionary and mechanistic causes.The New phytologist · 2021Review
- Pervasive Phenotypic Impact of a Large Nonrecombining Introgressed Region in Yeast.Molecular biology and evolution · 2020Article
- Differential Gene Expression between Fungal Mating Types Is Associated with Sequence Degeneration.Genome biology and evolution · 2020Article
- Little Evidence of Antagonistic Selection in the Evolutionary Strata of Fungal Mating-Type Chromosomes (G3 (Bethesda, Md.) · 2019Article
- Nuclear arms races: Experimental evolution for mating success in the mushroom-forming fungus Schizophyllum commune.PloS one · 2018Article
- Introgression maintains the genetic integrity of the mating-type determining chromosome of the fungus Neurospora tetrasperma.Genome research · 2016Article
- Article
- Contrasted patterns in mating-type chromosomes in fungi: hotspots versus coldspots of recombination.Fungal biology reviews · 2015Article
- Nuclear interactions in a heterokaryon: insight from the model Neurospora tetrasperma.Proceedings. Biological sciences · 2014Article
- Maintaining two mating types: structure of the mating type locus and its role in heterokaryosis in Podospora anserina.Genetics · 2014Article
- Gene expression differences among three Neurospora species reveal genes required for sexual reproduction in Neurospora crassa.PloS one · 2014Article
- Maintaining heterokaryosis in pseudo-homothallic fungi.Communicative & integrative biologyArticle
Corrections and comments
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Authors and funding
10 authors at 5 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
In the filamentous ascomycete Neurospora tetrasperma, a large (approx. 7 Mbp) region of suppressed recombination surrounds the mating-type (mat) locus. While the remainder of the genome is largely homoallelic, this region of recombinational suppression, extending over 1500 genes, is associated with sequence divergence. Here, we used microarrays to examine how the molecular phenotype of gene expression level is linked to this divergent region, and thus to the mating type. Culturing N. tetrasperma on agar media that induce sexual/female or vegetative/male tissue, we found 196 genes significantly differentially expressed between mat A and mat a mating types. Our data show that the genes exhibiting mat-linked expression are enriched in the region genetically linked to mating type, and sequence and expression divergence are positively correlated. Our results indicate that the phenotype of mat A strains is optimized for traits promoting sexual/female development and the phenotype of mat a strains for vegetative/male development. This discovery of differentially expressed genes associated with mating type provides a link between genotypic and phenotypic divergence in this taxon and illustrates a fungal analogue to sexual dimorphism found among animals and plants.
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