ArticleJournal of the peripheral nervous system : JPNS2013
Transitioning outcome measures: relationship between the CMTPedS and CMTNSv2 in children, adolescents, and young adults with Charcot-Marie-Tooth disease.
Article in Journal of the peripheral nervous system : JPNS, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
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Who cites it
11 citing papers in PubMed, 20 citations in OpenAlex.
- Asymmetric Cavovarus Deformity Presentation in Charcot-Marie-Tooth Disease.Foot & ankle orthopaedics · 2026Article
- Clinical Characteristics of Charcot-Marie-Tooth Disease Type 4J.Neurology · 2024Article
- A study concept of expeditious clinical enrollment for genetic modifier studies in Charcot-Marie-Tooth neuropathy 1A.Journal of the peripheral nervous system : JPNS · 2024Article
- Refining clinical trial inclusion criteria to optimize the standardized response mean of the CMTPedS.Annals of clinical and translational neurology · 2020Article
- Case series: Childhood Charcot-Marie-Tooth: Predominance of axonal subtype.eNeurologicalSci · 2019Article
- Characterizing postural oscillation in children and adolescents with hereditary sensorimotor neuropathy.PloS one · 2018Article
- A Rasch Analysis of the Charcot-Marie-Tooth Neuropathy Score (CMTNS) in a Cohort of Charcot-Marie-Tooth Type 1A Patients.PloS one · 2017Article
- Phenotypic Variability of Childhood Charcot-Marie-Tooth Disease.JAMA neurology · 2016Article
- Vincristine-induced peripheral neuropathy in pediatric cancer patients.American journal of cancer research · 2016Review
- Coexistence of a T118M PMP22 missense mutation and chromosome 17 (17p11.2-p12) deletion.Muscle & nerve · 2015Article
- Translation and cross-cultural adaptation of the Charcot-Marie-Tooth disease Pediatric Scale to Brazilian Portuguese and determination of its measurement properties.Brazilian journal of physical therapyArticle
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Authors and funding
14 authors at 8 institutions in 4 countries.
Funding
Abstract
Long-term studies of Charcot-Marie-Tooth (CMT) disease across the entire lifespan require stable endpoints that measure the same underlying construct (e.g., disability). The aim of this study was to assess the relationship between the CMT Pediatric Scale (CMTPedS) and the adult CMT Neuropathy Score (CMTNSv2) in 203 children, adolescents, and young adults with CMT. There was a moderate curvilinear correlation between the CMTPedS and the CMTNSv2 (Spearman's rho ρ = 0.716, p < 0.0001), although there appears to be a floor effect of the CMTNSv2 in patients with a milder CMT phenotype. Univariate analyses indicate that the relationship between the CMTPedS and CMTNSv2 scores improves with worsening disease severity and advancing age. Although one universal scale throughout life would be ideal, our data supports the transition from the CMTPedS in childhood to the CMTNSv2 in adulthood as a continuum of measuring lifelong disability in patients with CMT.
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