ArticleCanadian journal of gastroenterology = Journal canadien de gastroenterologie2013
The epidemiology of hepatitis C in a Canadian Indigenous population.
Article in Canadian journal of gastroenterology = Journal canadien de gastroenterologie, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers, 1 of them a synthesis that pooled it.
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Who cites it
26 citing papers in PubMed, 1 synthesis or guideline pooled it, 40 citations in OpenAlex.
- Hepatitis C Virus Infection in Indigenous Populations in the United States and Canada.Epidemiologic reviews · 2019Pooled it
- Article
- Epidemiology of Chronic Hepatitis C in First Nations Populations in Canadian Prairie Provinces.Pathogens (Basel, Switzerland) · 2025Review
- Hepatitis C (HCV) prevalence in citizens of the Métis Nation of Ontario.BMC infectious diseases · 2024Article
- Infectious diseases in Indigenous populations in North America: learning from the past to create a more equitable future.The Lancet. Infectious diseases · 2023Review
- Annual trends of hepatitis C virus infection in Manitoba between 1998 and 2018: A focus on special populations.Canadian liver journal · 2023Article
- Barriers and Facilitators to Hepatitis C Virus (HCV) Treatment for Aboriginal and Torres Strait Islander Peoples in Rural South Australia: A Service Providers' Perspective.International journal of environmental research and public health · 2023Article
- Lessons from First Nations partnerships in hepatitis C research and the co-creation of knowledge.Canadian liver journal · 2023Article
- ECHO+: Improving access to hepatitis C care within Indigenous communities in Alberta, Canada.Canadian liver journal · 2022Article
- The hepatitis C epidemic in Canada: An overview of recent trends in surveillance, injection drug use, harm reduction and treatment.Canada communicable disease report = Releve des maladies transmissibles au Canada · 2021Article
- Findings among Indigenous participants of the Tracks survey of people who inject drugs in Canada, Phase 4, 2017-2019.Canada communicable disease report = Releve des maladies transmissibles au Canada · 2021Article
- Differences among hepatitis C patients seen in community and specialist outpatient care settings.Canadian liver journal · 2020Article
- Polymorphisms in the P2X7 receptor, and differential expression of Toll-like receptor-mediated cytokines and defensins, in a Canadian Indigenous group.Scientific reports · 2019Article
- The distribution and socioeconomic burden of Hepatitis C virus in South Australia: a cross-sectional study 2010-2016.BMC public health · 2019Article
- Hepatitis C virus infection in Saskatchewan First Nations communities: Challenges and innovations.Canada communicable disease report = Releve des maladies transmissibles au Canada · 2018Article
- Review
- Contextualizing Canada's hepatitis C virus epidemic.Canadian liver journal · 2018Review
- In the eyes of Indigenous people in Canada: exposing the underlying colonial etiology of hepatitis C and the imperative for trauma-informed care.Canadian liver journal · 2018Article
- First Nations hepatitis C virus infections: Six-year retrospective study of on-reserve rates of newly reported infections in northwestern Ontario.Canadian family physician Medecin de famille canadien · 2017Article
- Favourable IFNL3 genotypes are associated with spontaneous clearance and are differentially distributed in Aboriginals in Canadian HIV-hepatitis C co-infected individuals.International journal of molecular sciences · 2015Article
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4 authors at 1 institution in 1 country.
Funding
Abstract
backgroundAn estimated 1% to 1.9% of North Americans are infected with the hepatitis C virus (HCV). Although Indigenous peoples are considered to bear the highest burden, there are only limited data regarding the demographic features and epidemiology of hepatitis C in this population.
objectivesTo document the demographic characteristics, rates of newly diagnosed hepatitis C cases and prevalence of HCV infection in a Canadian First Nations population, and to compare the findings with an infected non-First Nations population.
methodsA research database spanning 1991 to 2002 was developed, linking records from multiple clinical and administrative sources. Over a 12-year period, 671 First Nations and 4347 non-First Nations HCV-positive Canadians were identified in the province of Manitoba. Demographics, residence and time trends were compared between infected First Nations and non-First Nations persons.
resultsHCV-infected First Nations individuals were younger (mean [± SD] age 33.0±0.4 years versus 39.7±0.2 years; P<0.0001), more often female (60% versus 40%; P<0.0001) and more often resided in urban centres (73% versus 27%; P<0.001). The rate of newly diagnosed HCV cases was 2.5-fold (91.1 per 100,000 versus 36.6 per 100,000; P<0.000) and prevalence 2.4-fold (801.7 per 100,000 versus 334.8 per 100,000; P<0.000) higher among the First Nations relative to non-First Nations populations.
conclusionsThe results of the present large population-based study indicate that the First Nations population with hepatitis C is characteristically different from infected non-First Nations persons. The results also describe higher rates of newly diagnosed cases and prevalence of HCV infection in the First Nations population. These findings should serve as an important baseline for future primary prevention and therapeutic intervention strategies in this high-risk population.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.