Evidence map›Paper›PMID 23781468›Full record

ArticlePharmaceutical methods2011

Application of UV spectrophotometric method for easy and rapid estimation of lafutidine in bulk and pharmaceutical formulation.

Kiran Jadhav, Dinesh Dhamecha, Amol Tate, Harshad Tambe, Mrityunjaya B Patil

Abstract read
In one paragraph

Article in Pharmaceutical methods, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

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2citing papers in PubMed
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1 · What the graph read from it

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3 · Its place in the literature

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2 citing papers in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

5 authors.

Kiran JadhavDepartment of Pharmaceutical Analysis, Genba Sopanrao Moze College of Pharmacy, Wagholi, Pune, India.
Dinesh Dhamecha
Amol Tate
Harshad Tambe
Mrityunjaya B Patil

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionThe present research work discusses the development of a UV estimation method for lafutidine. Simple, accurate, cost efficient, and reproducible spectrophotometric method has been developed for the estimation of Lafutidine in bulk and pharmaceutical dosage form. MATERIALS AND

methodsThe Stock solution was prepared in a mixture of water and methanol (1:1). Further dilutions were made in water.

resultsThe drug was determined at maximum wavelength (λmax) 279 nm. Beers law was obeyed in the concentration range of 10-50 μg/ml having line equation y = 0.0100x + 0.035 with correlation coefficient of 0.999. Results of the analysis were validated statistically and by recovery study.

conclusionThe result of analysis was validated as per ICH guidelines and this method can be used for the routine analysis of lafutidine formulation.

Indexed as

LafutidineUV spectrophotometryvalidation

Identifiers

PMID23781468
PMCPMC3658075

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