ArticleInternational journal of medical sciences2013
Lyme borreliosis in human patients in Florida and Georgia, USA.
Article in International journal of medical sciences, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 39 papers, 1 of them a synthesis that pooled it.
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Who cites it
39 citing papers in PubMed, 1 synthesis or guideline pooled it, 89 citations in OpenAlex.
- Human pathogens associated with the blacklegged tick Ixodes scapularis: a systematic review.Parasites & vectors · 2016Pooled it
- Human Complement Evasion Is Widespread Among Lyme Borreliosis Spirochete Species.Pathogens (Basel, Switzerland) · 2026Article
- Broadly conserved protective epitopes on the lyme disease vaccine antigen, OspA.PLoS pathogens · 2026Article
- PCR Detection ofPathogens (Basel, Switzerland) · 2024Article
- Pathogenicity and virulence ofVirulence · 2023Review
- New geographical records for tick-borne pathogens in ticks collected from cattle in Benin and Togo.Veterinary medicine and science · 2023Article
- Epidemiological Survey of the Main Tick-Borne Pathogens Infecting Dogs from the Republic of Moldova.Pathogens (Basel, Switzerland) · 2022Article
- Musculoskeletal manifestations of Lyme borreliosis - a review.Archives of medical science : AMS · 2022Article
- Article
- Epidemiological Characteristics of Field Tick-Borne Pathogens in Gwang-ju Metropolitan Area, South Korea, from 2014 to 2018.Osong public health and research perspectives · 2020Article
- Classification and Staging of Morgellons Disease: Lessons from Syphilis.Clinical, cosmetic and investigational dermatology · 2020Article
- Chronic Lyme Disease: An Evidence-Based Definition by the ILADS Working Group.Antibiotics (Basel, Switzerland) · 2019Article
- MixedHealthcare (Basel, Switzerland) · 2019Article
- Amblyomma americanum (Acari: Ixodidae) Ticks Are Not Vectors of the Lyme Disease Agent, Borrelia burgdorferi (Spirocheatales: Spirochaetaceae): A Review of the Evidence.Journal of medical entomology · 2018Review
- Borrelia miyamotoi sensu lato in Père David Deer and Haemaphysalis longicornis Ticks.Emerging infectious diseases · 2018Article
- Persistent Borrelia Infection in Patients with Ongoing Symptoms of Lyme Disease.Healthcare (Basel, Switzerland) · 2018Article
- Article
- Better drugs for Lyme disease: focus on the spirochete.Infection and drug resistance · 2018Article
- Brave New Worlds: The Expanding Universe of Lyme Disease.Vector borne and zoonotic diseases (Larchmont, N.Y.) · 2017Review
- Metabolic differentiation of early Lyme disease from southern tick-associated rash illness (STARI).Science translational medicine · 2017Article
Corrections and comments
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The aim of this study was to determine the cause of illness in several human patients residing in Florida and Georgia, USA, with suspected Lyme disease based upon EM-like skin lesions and/or symptoms consistent with early localized or late disseminated Lyme borreliosis. Using polymerase chain reaction (PCR) assays developed specifically for Lyme group Borrelia spp., followed by DNA sequencing for confirmation, we identified Borrelia burgdorferi sensu lato DNA in samples of blood and skin and also in lone star ticks (Amblyomma americanum) removed from several patients who either live in or were exposed to ticks in Florida or Georgia. This is the first report to present combined PCR and DNA sequence evidence of infection with Lyme Borrelia spp. in human patients in the southern U.S., and to demonstrate that several B. burgdorferi sensu lato species may be associated with Lyme disease-like signs and symptoms in southern states. Based on the findings of this study, we suggest that human Lyme borreliosis occurs in Florida and Georgia, and that some cases of Lyme-like illness referred to as southern tick associated rash illness (STARI) in the southern U.S. may be attributable to previously undetected B. burgdorferi sensu lato infections.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.