ArticlemBio2013
Metaproteomics reveals abundant transposase expression in mutualistic endosymbionts.
Article in mBio, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
18 citing papers in PubMed, 34 citations in OpenAlex.
- Mosaic environment-driven evolution of the deep-sea mussel Gigantidas platifrons bacterial endosymbiont.Microbiome · 2023Article
- Metagenomic methylation patterns resolve bacterial genomes of unusual size and structural complexity.The ISME journal · 2022Article
- The life cycle-dependent transcriptional profile of the obligate intracellular amoeba symbiont Amoebophilus asiaticus.FEMS microbiology ecology · 2022Article
- Hologenome analysis reveals dual symbiosis in the deep-sea hydrothermal vent snail Gigantopelta aegis.Nature communications · 2021Article
- Article
- From sequence to information.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2020Review
- ANPELA: analysis and performance assessment of the label-free quantification workflow for metaproteomic studies.Briefings in bioinformatics · 2020Article
- Fueled by methane: deep-sea sponges from asphalt seeps gain their nutrition from methane-oxidizing symbionts.The ISME journal · 2019Article
- A Potential Role for Epigenetic Processes in the Acclimation Response to ElevatedFrontiers in microbiology · 2018Article
- High abundance and expression of transposases in bacteria from the Baltic Sea.The ISME journal · 2017Article
- Mixed transmission modes and dynamic genome evolution in an obligate animal-bacterial symbiosis.The ISME journal · 2017Article
- Proteomics informed by transcriptomics for characterising active transposable elements and genome annotation in Aedes aegypti.BMC genomics · 2017Article
- Proteomics technique opens new frontiers in mobilome research.Mobile genetic elements · 2017Article
- Metatranscriptomic Analysis Reveals Unexpectedly Diverse Microbial Metabolism in a Biogeochemical Hot Spot in an Alluvial Aquifer.Frontiers in microbiology · 2017Article
- Environmental Microbial Community Proteomics: Status, Challenges and Perspectives.International journal of molecular sciences · 2016Review
- Nutrients drive transcriptional changes that maintain metabolic homeostasis but alter genome architecture in Microcystis.The ISME journal · 2014Article
- Bacterial insertion sequences: their genomic impact and diversity.FEMS microbiology reviews · 2014Review
- The periodontal pathogen Porphyromonas gingivalis induces expression of transposases and cell death of Streptococcus mitis in a biofilm model.Infection and immunity · 2014Article
Corrections and comments
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Authors and funding
5 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Transposases, enzymes that catalyze the movement of mobile genetic elements, are the most abundant genes in nature. While many bacteria encode an abundance of transposases in their genomes, the current paradigm is that the expression of transposase genes is tightly regulated and generally low due to its severe mutagenic effects. In the current study, we detected the highest number of transposase proteins ever reported in bacteria, in symbionts of the gutless marine worm Olavius algarvensis with metaproteomics. At least 26 different transposases from 12 different families were detected, and genomic and proteomic analyses suggest that many of these are active. This high expression of transposases indicates that the mechanisms for their tight regulation have been disabled or no longer exist.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.