ArticleNeurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology2013
Herpes simplex encephalitis: clinical presentation, neurological sequelae and new prognostic factors. Ten years of experience.
Article in Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.
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Who cites it
24 citing papers in PubMed, 66 citations in OpenAlex.
- Trial
- Research trends on herpes simplex encephalitis in children: a bibliometric analysis from 1975 to 2024.Translational pediatrics · 2025Article
- Sequelae of viral CNS infections including outcomes, mechanisms, and knowledge gaps.Npj viruses · 2025Review
- Shared interactions of six neurotropic viruses with 38 human proteins: a computational and literature-based exploration of viral interactions and hijacking of human proteins in neuropsychiatric disorders.Discover mental health · 2025Article
- Herpes simplex encephalitis in France: incidence, 6-month rehospitalizations and mortality.Infection · 2024Article
- Can we forecast poor outcome in herpes simplex and varicella zoster encephalitis? A narrative review.Frontiers in neurology · 2023Review
- Dataset of a retrospective multicenter cohort study on characteristics of immune checkpoint inhibitor-induced encephalitis and comparison with HSV-1 and anti-LGI1 encephalitis.Data in brief · 2022Article
- Herpetic encephalitis: which treatment for which body weight?Journal of neurology · 2022Article
- Adult-onset mitochondrial encephalomyopathy, lactic acidosis and stroke-like episodes (MELAS) syndrome with progressive sensorineural hearing loss: A case report.Radiology case reports · 2021Article
- Prevalence and clinical manifestations of herpes simplex virus infection among suspected patients of herpes simplex encephalitis in Shiraz, Iran.Virusdisease · 2021Article
- The Hippocampal Vulnerability to Herpes Simplex Virus Type I Infection: Relevance to Alzheimer's Disease and Memory Impairment.Frontiers in cellular neuroscience · 2021Review
- A Cross-Sectional Study of Hyponatremia Associated with Acute Central Nervous System Infections.Journal of clinical medicine · 2019Article
- Functional outcomes in adult patients with herpes simplex encephalitis admitted to the ICU: a multicenter cohort study.Intensive care medicine · 2019Article
- Herpes Simplex Virus Type 1 Infection of the Central Nervous System: Insights Into Proposed Interrelationships With Neurodegenerative Disorders.Frontiers in cellular neuroscience · 2019Review
- Herpes encephalitis : a stroke mimicker.Journal of community hospital internal medicine perspectives · 2019Article
- Herpes Simplex Virus Encephalitis: Atypical Presentation as a Right Middle Cerebral Artery Stroke.Cureus · 2018Article
- Burden of herpes simplex virus encephalitis in the United States.Journal of neurology · 2017Article
- Herpes Simplex Encephalitis: an Update.Current infectious disease reports · 2017Review
- Herpes Simplex Virus-1 Encephalitis in Adults: Pathophysiology, Diagnosis, and Management.Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics · 2016Review
- Validity of the coding for herpes simplex encephalitis in the Danish National Patient Registry.Clinical epidemiology · 2016Article
Corrections and comments
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Authors and funding
5 authors at 4 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Herpes simplex encephalitis (HSE) is the most important viral encephalitis due to its high mortality and neurological sequelae. The aim of this study was to contribute to better characterise the HSE. We retrospectively analysed patients with a diagnosis of HSE in our hospital during 2000 and 2010. We included those patients who had a positive result for PCR for herpes simplex virus in cerebrospinal fluid and those with a negative result presenting with a consistent clinical and neuroimage profile. We included 26 patients (10 men, 16 women). Mean age was 58 years. Most frequent symptoms at admission were fever, confusion, aphasia and seizures. Mortality rate was 11 %. 2 patients presented a clinical relapse. In conclusion, the most frequent neurological sequelae were aphasia and amnesia. Disorientation, hyponatremia and abnormalities in initial brain CT were identified as new prognostic factors.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.