ArticleJournal of biomedical optics2013
Phantoms for diffuse optical imaging based on totally absorbing objects, part 1: Basic concepts.
Article in Journal of biomedical optics, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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Who cites it
14 citing papers in PubMed, 42 citations in OpenAlex.
- Phantom for standardization in functional near-infrared spectroscopy, part 1: implementation and usage.Neurophotonics · 2025Article
- Emulation of Brain Metabolic Activities Based on a Dynamically Controllable Optical Phantom.Cyborg and bionic systems (Washington, D.C.) · 2023Article
- Multi-modulated frequency domain high density diffuse optical tomography.Biomedical optics express · 2022Article
- Multi-laboratory performance assessment of diffuse optics instruments: the BitMap exercise.Journal of biomedical optics · 2022Article
- Wearable and wireless time-domain near-infrared spectroscopy system for brain and muscle hemodynamic monitoring.Biomedical optics express · 2020Article
- Instrumental, optical and geometrical parameters affecting time-gated diffuse optical measurements: a systematic study.Biomedical optics express · 2018Article
- Chromophore decomposition in multispectral time-resolved diffuse optical tomography.Biomedical optics express · 2017Article
- Quantification in time-domain diffuse optical tomography using Mellin-Laplace transforms.Biomedical optics express · 2016Article
- Towards next-generation time-domain diffuse optics for extreme depth penetration and sensitivity.Biomedical optics express · 2015Article
- Interstitial diffuse radiance spectroscopy of gold nanocages and nanorods in bulk muscle tissues.International journal of nanomedicine · 2015Article
- Multi-channel medical device for time domain functional near infrared spectroscopy based on wavelength space multiplexing.Biomedical optics express · 2013Article
- Method for the discrimination of superficial and deep absorption variations by time domain fNIRS.Biomedical optics express · 2013Article
- Tagging photons with gold nanoparticles as localized absorbers in optical measurements in turbid media.Biomedical optics express · 2013Article
- MAESTROS: A Multiwavelength Time-Domain NIRS System to Monitor Changes in Oxygenation and Oxidation State of Cytochrome-C-Oxidase.IEEE journal of selected topics in quantum electronics : a publication of the IEEE Lasers and Electro-optics SocietyArticle
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Authors and funding
9 authors at 6 institutions in 3 countries.
Funding
Abstract
The design of inhomogeneous phantoms for diffuse optical imaging purposes using totally absorbing objects embedded in a diffusive medium is proposed and validated. From time-resolved and continuous-wave Monte Carlo simulations, it is shown that a given or desired perturbation strength caused by a realistic absorbing inhomogeneity of a certain absorption and volume can be approximately mimicked by a small totally absorbing object of a so-called equivalent black volume (equivalence relation). This concept can be useful in two ways. First, it can be exploited to design realistic inhomogeneous phantoms with different perturbation strengths simply using a set of black objects with different volumes. Further, it permits one to grade physiological or pathological changes on a reproducible scale of perturbation strengths given as equivalent black volumes, thus facilitating the performance assessment of clinical instruments. A set of plots and interpolating functions to derive the equivalent black volume corresponding to a given absorption change is provided. The application of the equivalent black volume concept for grading different optical perturbations is demonstrated for some examples.
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