ArticleClinics (Sao Paulo, Brazil)2013
Fatal pulmonary embolism in hospitalized patients: a large autopsy-based matched case-control study.
Article in Clinics (Sao Paulo, Brazil), 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
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Who cites it
5 citing papers in PubMed, 12 citations in OpenAlex.
- Microscopic vessel caliber patterns in pulmonary thromboembolism: Clinical and autopsy correlations in a 10-year autopsy series.Forensic science, medicine, and pathology · 2026Article
- The Positive Rate of Pulmonary Embolism by CT Pulmonary Angiography Is High in an Emergency Department, Even in Low-Risk or Young Patients.Medical principles and practice : international journal of the Kuwait University, Health Science Centre · 2021Article
- Histological criteria for age determination of fatal venous thromboembolism.International journal of legal medicine · 2018Article
- Prevalence of pulmonary embolism at autopsy among elderly patients in a Chinese general hospital.Journal of geriatric cardiology : JGC · 2016Article
- Venous thromboembolism in Latin America: a review and guide to diagnosis and treatment for primary care.Clinics (Sao Paulo, Brazil) · 2016Review
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Authors and funding
8 authors at 1 institution in 1 country.
Funding
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Abstract
objectivePulmonary embolism is an underdiagnosed major cause of death for hospitalized patients. The objective of this study was to identify the conditions associated with fatal pulmonary embolism in this population.
methodsA total of 13,074 autopsy records were evaluated in a case-control study. Patients were matched by age, sex, and year of death, and factors potentially associated with fatal pulmonary embolism were analyzed using univariate and multivariate conditional logistic regression.
resultsPulmonary embolism was considered fatal in 328 (2.5%) patients. In the multivariate analysis, conditions that were more common in patients who died of pulmonary embolism were atherosclerosis, congestive heart failure, and neurological surgery. Some conditions were negatively associated with fatal pulmonary embolism, including hemorrhagic stroke, aortic aneurism, cirrhosis, acquired immune deficiency syndrome, and pneumonia. In the control group, patients with hemorrhagic stroke and aortic aneurism had short hospital stays (8.5 and 8.8 days, respectively), and the hemorrhage itself was the main cause of death in most of them (90.6% and 68.4%, respectively), which may have prevented the development of pulmonary embolism. Cirrhotic patients in the control group also had short hospital stays (7 days), and 50% died from bleeding complications.
conclusionsIn this large autopsy study, atherosclerosis, congestive heart failure, and neurological surgery were diagnoses associated with fatal pulmonary embolism.
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