Evidence map›Paper›PMID 23778244›Full record

ReviewThe Analyst2013

Recent advances in microfluidic cell separations.

Yan Gao, Wenjie Li, Dimitri Pappas

Abstract readReview
In one paragraph

Review in The Analyst, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
6.4field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 73 citations in OpenAlex.

  1. Article
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  4. Microfluidic Approaches for Affinity-Based Exosome Separation.International journal of molecular sciences · 2022
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Yan GaoDepartment of Chemistry and Biochemistry, Texas Tech University, Lubbock, Texas 79409, USA.
Wenjie Li
Dimitri Pappas
Texas Tech University · US

Funding

Rapid Single Molecule Detection System for Intracellular Protease ActivityR21RR025782 · NCRR · TEXAS TECH UNIVERSITY · PI PAPPAS, DIMITRI · 2010 to 2011
$346k
Rapid Single Molecule Detection System for Intracellular Protease ActivityR21GM103550 · NIGMS · TEXAS TECH UNIVERSITY · PI PAPPAS, DIMITRI · 2012 to 2012
$172k
NCRR NIH HHS R21 RR025782NCRR NIH HHS RR025782NIGMS NIH HHS GM103550NIGMS NIH HHS R21 GM103550
6 · The paper itself

Abstract

The isolation and sorting of cells has become an increasingly important step in chemical and biological analyses. As a unit operation in more complex analyses, isolating a phenotypically pure cell population from a heterogeneous sample presents unique challenges. Microfluidic systems are ideal platforms for performing cell separations, enabling integration with other techniques and enhancing traditional separation modalities. In recent years there have been several techniques that use surface antigen affinity, physical interactions, or a combination of the two to achieve high separation purity and efficiency. This review discusses methods including magnetophoretic, acoustophoretic, sedimentation, electric, and hydrodynamic methods for physical separations. We also discuss affinity methods, including magnetic sorting, flow sorting, and affinity capture.

Indexed as

Affinity LabelsAnimalsCell SeparationHumansMicrofluidic Analytical TechniquesPhysical PhenomenaAffinity Labels

Identifiers

PMID23778244
PMCPMC3739304
OpenAlexW2057052704

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.