Evidence map›Paper›PMID 23777977›Full record

ReviewCritical reviews in oncology/hematology2013

Lymphedema following treatment for breast cancer: a new approach to an old problem.

Jean O'Toole, Lauren S Jammallo, Melissa N Skolny, Cynthia L Miller, Krista Elliott, Michelle C Specht, Alphonse G Taghian

Registry-linked trialAbstract readReview
In one paragraph

Review in Critical reviews in oncology/hematology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06572098 (The Effect of Complex Decongestıve Therapy on Oxıdatıve Stress and Antıoxıdants In Patıents Wıth Lymphedema After Breast Cancer Treatment), which is not on this map. Cited by 22 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06572098 naenrolling by invitationnot on this mapstarted 2024, after this paper: background citation

The Effect of Complex Decongestıve Therapy on Oxıdatıve Stress and Antıoxıdants In Patıents Wıth Lymphedema After Breast Cancer Treatment

TypeinterventionalSponsorBaskent UniversityRan2024 to 2028Enrolled52ConditionsWhat Are the Effects of Lymphedema TreatmentArmsComplex decongestive therapy
3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Guideline
  2. Trial
  3. Article
  4. Article
  5. Observational
  6. Article
  7. Article
  8. Article
  9. Article
  10. Review
  11. Article
  12. Article
  13. Observational
  14. Article
  15. Association Between Precautionary Behaviors and Breast Cancer-Related Lymphedema in Patients Undergoing Bilateral Surgery.Journal of clinical oncology : official journal of the American Society of Clinical Oncology · 2017
    Article
  16. Diagnosis of Upper-Quadrant Lymphedema Secondary to Cancer: Clinical Practice Guideline From the Oncology Section of APTA.Rehabilitation oncology (American Physical Therapy Association. Oncology Section) · 2017
    Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Jean O'TooleDepartment of Physical and Occupational Therapy, Massachusetts General Hospital, Boston, MA 02114, United States.
Lauren S Jammallo
Melissa N Skolny
Cynthia L Miller
Krista Elliott
Michelle C Specht
Alphonse G Taghian

Funding

Variation in Receptor Tyrosine Kinases and Breast Cancer RiskP50CA089393 · NCI · DANA-FARBER CANCER INSTITUTE · PI HARRIS, LYNDSAY NORINE · 2000 to 2009
$28.8M
Early Detection and Treatment of Lymphedema in Women with Breast CancerR01CA139118 · NCI · MASSACHUSETTS GENERAL HOSPITAL · PI TAGHIAN, ALPHONSE G · 2009 to 2013
$1.4M
NCI NIH HHS P50 CA089393NCI NIH HHS P50CA089393NCI NIH HHS R01 CA139118NCI NIH HHS R01CA139118
6 · The paper itself

Abstract

Lymphedema following treatment for breast cancer can be an irreversible condition with a profound negative impact on quality of life. The lack of consensus regarding standard definitions of clinically significant lymphedema and optimal methods of measurement and quantification are unresolved problems. Inconsistencies persist regarding the appropriate timing of intervention and what forms of treatment should be the standard of care. There are reports that early detection and intervention can prevent progression, however,the Level 1 evidence to support this hypothesis has yet to be generated. To assess these controversies, we propose the implementation of a screening program to detect early lymphedema in conjunction with a randomized, prospective trial designed to generate Level 1 evidence regarding the efficacy of early intervention and appropriate treatment strategies. Collaboration among institutions that manage breast cancer patients is essential to establish a standardized approach to lymphedema and to establish guidelines for best practice.

Indexed as

Breast NeoplasmsFemaleHumansLymphedemaQuality of LifeTime FactorsBreast cancerLymphedemaPerometerScreening

Identifiers

PMID23777977
PMCPMC3784614

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.