Evidence map›Paper›PMID 23776717›Full record

ArticleInternational journal of preventive medicine2013

A literature review on the efficacy and safety of botulinum toxin: an injection in post-stroke spasticity.

Majid Ghasemi, Mehri Salari, Fariborz Khorvash, Vahid Shaygannejad

Registry-linked trialAbstract read
In one paragraph

Article in International journal of preventive medicine, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02074150 (ASIS for Botox in Upper Limb Spasticity), which is not on this map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02074150 phase1 / phase2unknown statusnot on this mapstarted 2016, after this paper: background citation

ASIS for Botox in Upper Limb Spasticity

TypeinterventionalSponsorli nguyenRan2016 to 2017Enrolled60ConditionsUpper Limb Spasticity Unilaterally in Adults With History of Stroke, Increased Muscle Tone in Elbow, Wrist, Finger, and Thumb Flexors.ArmsGadolinium, Efficacy of Botox intramuscularly at Week 6, Efficacy of Botox intramuscularly at Week 12,, Efficacy of Botox intramuscularly at Week 18, Efficacy of Botox intramuscularly at Week 24
3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. High doses of onabotulinumtoxinA in post-stroke spasticity: a retrospective analysis.Journal of neural transmission (Vienna, Austria : 1996) · 2015
    Article
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Majid GhasemiDepartment of Neurology, Isfahan Neurosciences Research Center, Isfahan University of Medical Sciences, Isfahan, Iran.
Mehri Salari
Fariborz Khorvash
Vahid Shaygannejad

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundA variety of techniques for the management of spasticity have been suggested, including positioning, cryotherapy, splinting and casting, biofeedback, electrical stimulation, and medical management by pharmacological agents, Botulinum toxin A (BTA) is now the pharmacological treatment of choice in focal spasticity. BTA by blocking acetylcholine release at neuromuscular junctions accounts for its therapeutic action to relieve spasticity.

methodsA computerized search of Pub Med was carried out to find the latest result about efficacy of BTA in management of post stroke spasticity.

resultAmong 84 articles were found, frothy of them included in this review and divided to lower and upper extremity.

conclusionsBTA is a treatment choice in reducing tone and managing post stroke spasticity .

Indexed as

Botulinum toxin Aspasticitystroke

Identifiers

PMID23776717
PMCPMC3678211

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.