ArticlePloS one2013
Population structure and evolution of non-O1/non-O139 Vibrio cholerae by multilocus sequence typing.
Article in PloS one, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 57 papers.
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Who cites it
57 citing papers in PubMed.
- Whole Genome Characterisation of Non-O1/Non-O139Microorganisms · 2026Article
- Population structure and phylogenetic analysis of Vibrio cholerae non-O1/O139 by whole genome sequencing.PloS one · 2026Article
- Genomic characterization of non-O1, non-O139 Vibrio cholerae causing rare clinical manifestation.BMC infectious diseases · 2025Article
- Genomics reveals multiple introductions of the seventh pandemicMicrobial genomics · 2025Article
- Genomic Analysis and Virulence Features of Vibrio cholerae Non-O1/Non-O139 Harbouring CARB-Type β-Lactamases From Freshwater Bodies, Argentina.Environmental microbiology reports · 2025Article
- Enigmatic roles ofJournal of bacteriology · 2025Review
- Genomic insights into clinical non-O1/non-O139Microbiology spectrum · 2025Article
- Vibrio cholerae endemic to the lower Rio Grande Delta segregate into urban and rural phylotypes.Scientific reports · 2025Article
- Antimicrobial resistance ofApplied and environmental microbiology · 2025Article
- Genomic characterization ofFrontiers in microbiology · 2025Article
- Think Vibrio, Think Rare: Non-O1-Non-O139-Tropical medicine and infectious disease · 2024Article
- Vibriocidal efficacy of Bifidobacterium bifidum and Lactobacillus acidophilus cell-free supernatants encapsulated in chitosan nanoparticles against multi-drug resistant Vibrio cholerae O1 El Tor.BMC infectious diseases · 2024Article
- Article
- Public health aspects ofEFSA journal. European Food Safety Authority · 2024Article
- Article
- Non-O1/Non-O139Microorganisms · 2024Review
- Genetic approach toward linkage of Iran 2012-2016 cholera outbreaks with 7th pandemic Vibrio cholerae.BMC microbiology · 2024Article
- Pathways of exposure to Vibrio Cholerae in an urban informal settlement in Nairobi, Kenya.PLOS global public health · 2024Article
- Emergence and genomic insights of non-pandemic O1Microbiology spectrum · 2023Article
- Vibrio cholerae-An emerging pathogen in Austrian bathing waters?Wiener klinische Wochenschrift · 2023Review
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Authors and funding
9 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Pathogenic non-O1/non-O139 Vibrio cholerae strains can cause sporadic outbreaks of cholera worldwide. In this study, multilocus sequence typing (MLST) of seven housekeeping genes was applied to 55 non-O1/non-O139 isolates from clinical and environmental sources. Data from five published O1 isolates and 17 genomes were also included, giving a total of 77 isolates available for analysis. There were 66 sequence types (STs), with the majority being unique, and only three clonal complexes. The V. cholerae strains can be divided into four subpopulations with evidence of recombination among the subpopulations. Subpopulations I and III contained predominantly clinical strains. PCR screening for virulence factors including Vibrio pathogenicity island (VPI), cholera toxin prophage (CTXΦ), type III secretion system (T3SS), and enterotoxin genes (rtxA and sto/stn) showed that combinations of these factors were present in the clinical isolates with 85.7% having rtxA, 51.4% T3SS, 31.4% VPI, 31.4% sto/stn (NAG-ST) and 11.4% CTXΦ. These factors were also present in environmental isolates but at a lower frequency. Five strains previously mis-identified as V. cholerae serogroups O114 to O117 were also analysed and formed a separate population with V. mimicus. The MLST scheme developed in this study provides a framework to identify sporadic cholera isolates by genetic identity.
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