Evidence map›Paper›PMID 23775752›Full record

ArticleMethods in molecular biology (Clifton, N.J.)2013

Discovery and customized validation of antibody targets by protein arrays and indirect ELISA.

Tara K Sigdel, Minnie M Sarwal

Abstract read
In one paragraph

Article in Methods in molecular biology (Clifton, N.J.), 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Tara K SigdelCalifornia Pacific Medical Center-Research Institute, San Francisco, CA, USA.
Minnie M Sarwal

Funding

Noninvasive Markers and Transplant Outcome in HumansU01AI063594 · NIAID · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI HEEGER, PETER SCOTT · 2004 to 2022
$66.5M
Urinary Proteome Monitoring for Transplant InjuryR01DK083447 · NIDDK · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI CAMP, DAVID G, SARWAL, MINNIE M · 2010 to 2013
$2.4M
NIAID NIH HHS U01 AI063594NIAID NIH HHS U01 AI063594-06NIDDK NIH HHS R01 DK083447NIDDK NIH HHS R01 DK083447-01A2
6 · The paper itself

Abstract

Because of our access to human genome data and ever improving genome sequencing and proteome analysis methods we are much better in terms of our understanding of biological processes. In addition to genomics, proteomics, and other "omics" methods, availability of more sophisticated molecular assaying methods have augmented our knowledge about immune processes towards autogeneic and allogeneic targets. High-density protein arrays are developed to analyze protein-small molecule interactions, enzyme-substrate profiling, protein-protein interaction, and immune monitoring by assessing antibodies in the serum.

Indexed as

Protein Array AnalysisAntibodiesBiomarkersEnzyme-Linked Immunosorbent AssayGenome, HumanHumansSmall Molecule LibrariesAntibodiesBiomarkersSmall Molecule Libraries

Identifiers

PMID23775752
PMCPMC4476239

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.