Evidence map›Paper›PMID 23775341›Full record

ArticleKnee surgery, sports traumatology, arthroscopy : official journal of the ESSKA2014

Orthopedic surgeons feel that there is a treatment gap in management of early OA: international survey.

Chuan Silvia Li, Jon Karlsson, Mitchell Winemaker, Parag Sancheti, Mohit Bhandari

Registry-linked trialAbstract read
PubMed Publisher
In one paragraph

Article in Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07036003 (Recombinant Human Growth Hormone), which is not on this map. Cited by 33 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
33citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07036003 phase1 / phase2active not recruitingnot on this mapstarted 2025, after this paper: background citation

Recombinant Human Growth Hormone (rHGH) for Knee Osteoarthritis (KORR): a Pilot, Randomized Placebo-controlled Trial

TypeinterventionalSponsorDr. David WassersteinRan2025 to 2029Enrolled34ConditionsKnee Osteoarthritis (Knee OA), Knee Osteoarthritis (OA)ArmsSomatropin (recombinant human growth hormone), bacteriostatic saline placebo
3 · Its place in the literature

Who cites it

33 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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  11. Patient-specific metal implants for focal chondral and osteochondral lesions in the knee; excellent clinical results at 2 years.Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA · 2021
    Observational
  12. Review
  13. Total knee replacement after high tibial osteotomy: time-to-event analysis and predictors.CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne · 2021
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Chuan Silvia LiGlobal Research Solutions Inc, Burlington, ON, Canada.
Jon Karlsson
Mitchell Winemaker
Parag Sancheti
Mohit Bhandari

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo understand orthopedic surgeons' views, preferences, and awareness on "treatment gap" and various conservative and surgical treatments for early to mid-stage knee osteoarthritis (OA).

methodsA self-administered questionnaire on the treatment of knee OA was developed in collaboration with orthopedic surgeons with extensive research experience and methodological expertise. The survey was distributed electronically to a group of international orthopedic surgeons and surgical trainees. The data were collected, reviewed, and analyzed using descriptive statistics.

resultsOne hundred and seventy-three surgeons and surgical trainees completed the survey. The respondents reported that about 58 % of the patients they treat have early to mid-stage knee OA (Kellgren and Lawrence grade I-III). There were significantly higher usage of medications and lower usage of unicompartmental knee arthroplasty (UKA) and total knee arthroplasty (TKA) (P < 0.05) in developing countries than in developed countries. Four of five surgeons (84 %) perceived a need for better treatments for younger (<60 years old) physically active OA patients in which UKA or TKA is not indicated. Most respondents (80 %) would be willing to adjust age/activity threshold for surgery if a procedure was reversible and recovery was minimal. Two of three surgeons (68.4 %) perceived a treatment gap for early knee OA. However, effective treatments for patients within the treatment gap would have substantial positive social, and economic impacts.

conclusionThe study suggests an ongoing treatment gap for patients with early knee OA and the need for better evidence to guide practice.

Indexed as

Attitude of Health PersonnelDeveloped CountriesDeveloping CountriesAdultAgedAge FactorsArthroplasty, Replacement, KneeFemaleHealth Care SurveysHumansMaleMiddle AgedOsteoarthritis, KneePractice Patterns, Physicians'Severity of Illness IndexSurveys and Questionnaires

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.