ArticleBreast cancer research and treatment2013
Clinicopathologic, mammographic, and sonographic features in 1,187 patients with pure ductal carcinoma in situ of the breast by estrogen receptor status.
Article in Breast cancer research and treatment, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.
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Who cites it
27 citing papers in PubMed.
- Preoperative breast MRI and long-term survival in ductal carcinoma in situ: a propensity score-weighted analysis.European radiology · 2026Article
- Multiparametric breast MRI to problem-solve mammographically detected suspicious calcifications.European journal of radiology · 2026Article
- Atraumatic Breast Fat Necrosis Mimicking Malignancy in End-Stage Renal Disease: A Case Report.The American journal of case reports · 2025Article
- Machine Learning Based on Digital Mammography to Reduce the Need for Invasive Biopsies of Benign Calcifications Classified in BI-RADS Category 4.Journal of imaging informatics in medicine · 2025Article
- Mitigating overtreatment of ductal carcinoma in situ.Radiology advances · 2025Review
- Role of MRI in the Diagnosis of Ductal Carcinoma In Situ: A Retrospective Study.Journal of clinical medicine · 2025Article
- An update on multimodal imaging strategies for nipple discharge: from detection to decision.Insights into imaging · 2025Article
- Integrating radiomics into predictive models for low nuclear grade DCIS using machine learning.Scientific reports · 2025Article
- Deep learning-based risk stratification of ductal carcinomaFrontiers in oncology · 2025Article
- The diagnostic value of contrast-enhanced ultrasound combined with clinicopathological features in microinvasive ductal carcinomaGland surgery · 2024Article
- AI analytics can be used as imaging biomarkers for predicting invasive upgrade of ductal carcinoma in situ.Insights into imaging · 2024Article
- Article
- Molecular Signatures in Ductal Carcinoma In Situ (DCIS): A Systematic Review and Meta-Analysis.Journal of clinical medicine · 2023Review
- Is palpable DCIS more aggressive than screen-detected DCIS?Surgery open science · 2023Article
- Prediction model of axillary lymph node status using automated breast ultrasound (ABUS) and ki-67 status in early-stage breast cancer.BMC cancer · 2022Article
- Ductal Carcinoma in Situ: State-of-the-Art Review.Radiology · 2022Review
- Variability in grading of ductal carcinoma in situ among an international group of pathologists.The journal of pathology. Clinical research · 2021Article
- Imaging of Noncalcified Ductal CarcinomaJournal of clinical imaging science · 2021Article
- Early diagnosis of breast cancer from exhaled breath by gas chromatography-mass spectrometry (GC/MS) analysis: A prospective cohort study.Journal of clinical laboratory analysis · 2020Article
- A review of the influence of mammographic density on breast cancer clinical and pathological phenotype.Breast cancer research and treatment · 2019Review
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11 authors.
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Abstract
The clinicopathologic, mammographic, and sonographic findings in patients with pure ductal carcinoma in situ (DCIS) were assessed by estrogen receptor (ER) expression. After institutional review board approval, patients with pure DCIS evaluated from January 1996 to July 2009 with known ER status and available imaging were identified. Images were reviewed as per the ACR BI-RADS(®) lexicon (4th edition). Clinical, pathologic, and imaging characteristics were analyzed by ER status using t test, Chi square test, and Fisher's exact test. Of 1,219 patients with pure DCIS and known ER status identified, 1,187 with complete data were included. Mammography was performed in all 1,187 patients and sonography in 519 (44 %). There were 972 (82 %) patients with ER-positive and 215 (18 %) with ER-negative disease. ER-negative DCIS was more likely to be high grade (93 vs 44 %, p < 0.0001), associated with comedonecrosis (64 vs 29 %, p < 0.0001), and multifocal (23 vs 15 %, p = 0.009). On sonography, ER-negative DCIS was more likely to be visible (61 vs 46 %, p = 0.004), larger (mean size, 2.3 vs 1.6 cm, p = 0.006), and show posterior shadowing (53 vs 28 %, p = 0.006). Mastectomy was more frequently performed for ER-negative DCIS (47 vs 37 %, p = 0.008). Palpable DCIS was visible on sonography in 55 % of cases and mammography in 81 %. Compared with ER-positive palpable DCIS, ER-negative palpable DCIS was larger and more likely to be visible on sonography. Compared with ER-positive noncalcified DCIS, ER-negative noncalcified DCIS was less likely to be visible on mammography. ER-positive and ER-negative pure DCIS have different clinicopathologic and imaging characteristics. ER-negative DCIS is associated with worse prognostic factors than ER-positive DCIS. On sonography, ER-negative DCIS is more frequently visible than ER-positive DCIS, tends to be larger, and more frequently demonstrates posterior shadowing.
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