Evidence map›Paper›PMID 23773849›Full record

ArticleExperimental and molecular pathology2013

Balloon liver cells forming Mallory-Denk-bodies are progenitor cells.

S W French, E Vitocruz, B A French

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Experimental and molecular pathology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
1.7field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 6 citations in OpenAlex.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

S W FrenchDepartment of Pathology, Harbor-UCLA Medical Center, Torrance, CA 90509, USA. sfrench@labiomed.org
E Vitocruz
B A French
Harbor–UCLA Medical Center · USUCLA Medical Center · US

Funding

ALCOHOLIC HEPATITIS PATHOGENESIS AS DETERMINED FROM HUMAN LIVER TISSUE ANALYSISU01AA021898 · NIAAA · LUNDQUIST INSTITUTE FOR BIOMEDICAL INNOVATION AT HARBOR-UCLA MEDICAL CENTER · PI FRENCH, SAMUEL WILLIAM · 2013 to 2017
$1.0M
NIAAA NIH HHS U01 AA021898PHS HHS P50-011999-14PHS HHS R01020585-01
6 · The paper itself

Abstract

Previous studies on both human and mice livers showed MDB formation in both drug hepatitis and hepatocellular carcinoma. Using the drug hepatitis mouse model of MDB formation, numerous markers for progenitor cells were found in the cells forming MDBs. In current study, using the drug hepatitis mouse model, we found that the MDB forming cells expressed two additional progenitor cell markers. These markers were CD49f and TLR4.

Indexed as

Mallory BodiesCase-Control StudiesHepatitis, AlcoholicHumansIntegrin alpha1LiverStem CellsToll-Like Receptor 4Integrin alpha1TLR4 protein, humanToll-Like Receptor 4Integrin alpha 6 (CD49f)Mallory–Denk bodies (MDBs)Progenitor cellsToll-like receptor 4 (TLR4)Tumor-initiating stem-like cells (TISC)

Identifiers

PMID23773849
PMCPMC3886363
OpenAlexW2008715581

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.