Evidence map›Paper›PMID 23773187›Full record

ArticleActa psychiatrica Scandinavica2014

Antidepressants and the risk of suicide in young persons--prescription trends and toxicological analyses.

G Isacsson, J Ahlner

Open access · hybridAbstract readComparative Study
In one paragraph

Article in Acta psychiatrica Scandinavica, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 1 pooled it
6.0field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 1 synthesis or guideline pooled it, 37 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 1 country.

G IsacssonDepartment of Clinical Neuroscience, Division of Psychiatry, Karolinska Institutet, Psychiatry Southwest, Karolinska University Hospital-Huddinge, Stockholm, Sweden.
J Ahlner
Karolinska Institutet · SESwedish National Board of Forensic Medicine · SE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo assess trends in the use of antidepressants among young suicides after the warning that these drugs might increase the risk of suicide.

methodIndividual data of all 845 suicides in the 10- to 19-year age group in Sweden in the time period 1992-2003 (baseline), and in 2004-2010 (after the warning). Outcome data are prescriptions of antidepressants prior to death and detections of antidepressants in post-mortem toxicology.

resultsAfter the warning, suicide in this age group increased for five consecutive years (60.5%). The increase occurred among individuals not treated with antidepressants.

conclusionThis study provides further support for the hypothesis that the warning, contrary to its intention, may have increased young suicides by leaving a number of suicidal young persons without treatment with antidepressants.

Indexed as

AdolescentAdultAntidepressive AgentsAutopsyChildDepressionDrug PrescriptionsFemaleHumansMaleRiskSuicideSwedenYoung AdultAntidepressive Agentsadolescentantidepressantsforensic toxicologysuicide

Identifiers

PMID23773187
PMCPMC4224008
OpenAlexW2000204913

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.