Evidence map›Paper›PMID 23772872›Full record

ArticleJournal of the American Geriatrics Society2013

Modifiable risk factors for pneumonia requiring hospitalization of community-dwelling older adults: the Health, Aging, and Body Composition Study.

Manisha Juthani-Mehta, Nathalie De Rekeneire, Heather Allore, Shu Chen, John R O'Leary, Douglas C Bauer, Tamara B Harris, Anne B Newman, Sachin Yende, Robert J Weyant and 3 more

Open access · greenAbstract read
In one paragraph

Article in Journal of the American Geriatrics Society, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
31citing papers in PubMed, 1 pooled it
13.4field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

31 citing papers in PubMed, 1 synthesis or guideline pooled it, 71 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Review
  8. Review
  9. Article
  10. Article
  11. Pneumonia prevention in the elderly patients: the other sides.Aging clinical and experimental research · 2021
    Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Biological Age, Not Chronological Age, Is Associated with Late-Life Depression.The journals of gerontology. Series A, Biological sciences and medical sciences · 2018
    Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 5 institutions in 1 country.

Manisha Juthani-MehtaSection of Infectious Diseases, Department of Internal Medicine, School of Medicine, Yale University, New Haven, Connecticut 06520, USA. manisha.juthani@yale.edu
Nathalie De Rekeneire
Heather Allore
Shu Chen
John R O'Leary
Douglas C Bauer
Tamara B Harris
Anne B Newman
Sachin Yende
Robert J Weyant
Stephen Kritchevsky
Vincent Quagliarello
Health ABC Study
Yale University · USUniversity of Pittsburgh · USNational Institute on Aging · USUniversity of California, San Francisco · USWake Forest University · US

Funding

YALE UNIVERSITY CLINICAL AND TRANSLATIONAL SCIENCE AWARD PROGRAMUL1RR024139 · NCRR · YALE UNIVERSITY · PI SHERWIN, ROBERT S · 2006 to 2011
$56.8M
Yale Study Support Suite (YES3): Dashboard and Web Portal Software Supporting Research Workflow through integrated, customizable REDCap External ModulesP30AG021342 · NIA · YALE UNIVERSITY · PI Albert C Shaw · 2002 to 2026
$37.9M
A Randomized Controlled Trial to Reduce Pneumonia in Nursing Home ResidentsR01AG030575 · NIA · YALE UNIVERSITY · PI QUAGLIARELLO, VINCENT JAMES · 2009 to 2013
$6.3M
Health, Aging and Body Composition StudyZIAAG007390 · NIA · NATIONAL INSTITUTE ON AGING · PI LAUNER, LENORE J · 2009 to 2024
$4.0M
Peripheral Nerve Function Decline in an Aged CohortR01AG028050 · NIA · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI STROTMEYER, ELSA S. · 2007 to 2015
$3.5M
End of Life in the Very OldR01NR012459 · NINR · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI ALBERT, STEVEN M, LUNNEY, JUNE R · 2011 to 2015
$2.7M
DYNAMICS OF HEALTH .AGING . AND BODY COMPOSITION /Pittsburgh/-260962101N01AG062101 · NIA · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · 1996 to 2004
$996k
UTI in Nursing Home Residents: Research Training and Clinical InvestigationK23AG028691 · NIA · YALE UNIVERSITY · PI JUTHANI-MEHTA, MANISHA · 2008 to 2012
$799k
DYNAMICS OF HEALTH . AGING . AND BODY COMPOSITION /Memphis/-26062103N01AG062103 · NIA · UNIVERSITY OF TENNESSEE HEALTH SCI CTR · 1996 to 2004
$793k
Program of Research in Infectious Diseases of EldersK07AG030093 · NIA · YALE UNIVERSITY · PI QUAGLIARELLO, VINCENT JAMES · 2010 to 2014
$672k
HEALTH ABC--COORDINATING UNIT /California/-260062106N01AG062106 · NIA · UNIVERSITY OF CALIFORNIA SAN FRANCISCO · 1996 to 2004
$109k
Intramural NIH HHSNCRR NIH HHS UL1 RR024139NIA NIH HHS K07 AG030093NIA NIH HHS K23 AG028691NIA NIH HHS N01 AG062101NIA NIH HHS N01 AG062103NIA NIH HHS N01 AG062106NIA NIH HHS N01-AG-6-2101NIA NIH HHS N01-AG-6-2103NIA NIH HHS N01-AG-6-2106NIA NIH HHS P30 AG021342NIA NIH HHS P30 AG21342NIA NIH HHS R01 AG028050NIA NIH HHS R01-AG028050NIA NIH HHS R01 AG030575NINR NIH HHS R01 NR012459NINR NIH HHS R01-NR012459
6 · The paper itself

Abstract

objectivesTo identify novel modifiable risk factors, focusing on oral hygiene, for pneumonia requiring hospitalization of community-dwelling older adults.

designProspective observational cohort study.

settingMemphis, Tennessee, and Pittsburgh, Pennsylvania.

participantsOf 3,075 well-functioning community-dwelling adults aged 70 to 79 enrolled in the Health, Aging, and Body Composition Study from 1997 to 1998, 1,441 had complete data in the data set of all variables used, a dental examination within 6 months of baseline, and were eligible for this study. MEASUREMENTS: The primary outcome was pneumonia requiring hospitalization through 2008.

resultsOf 1,441 participants, 193 were hospitalized for pneumonia. In a multivariable model, male sex (hazard ratio (HR) = 2.07, 95% confidence interval (CI) = 1.51-2.83), white race (HR = 1.44, 95% CI = 1.03-2.01), history of pneumonia (HR = 3.09, 95% CI = 1.86-5.14), pack-years of smoking (HR = 1.006, 95% CI = 1.001-1.011), and percentage of predicted forced expiratory volume in 1 minute (moderate vs mild lung disease or normal lung function, HR = 1.78, 95% CI = 1.28-2.48; severe lung disease vs mild lung disease or normal lung function, HR = 2.90, 95% CI = 1.51-5.57) were nonmodifiable risk factors for pneumonia. Incident mobility limitation (HR = 1.77, 95% CI = 1.32-2.38) and higher mean oral plaque score (HR = 1.29, 95% CI = 1.02-1.64) were modifiable risk factors for pneumonia. Average attributable fractions revealed that 11.5% of cases of pneumonia were attributed to incident mobility limitation and 10.3% to a mean oral plaque score of 1 or greater.

conclusionIncident mobility limitation and higher mean oral plaque score were two modifiable risk factors that 22% of pneumonia requiring hospitalization could be attributed to. These data suggest innovative opportunities for pneumonia prevention among community-dwelling older adults.

Indexed as

HospitalizationOral HygieneAgedCommunity-Acquired InfectionsComorbidityDental Plaque IndexFemaleGeriatric AssessmentHumansIncidenceMalePennsylvaniaPneumoniaProportional Hazards ModelsProspective StudiesRisk Factorscommunity-dwellingpneumoniarisk factors

Identifiers

PMID23772872
PMCPMC3714374
OpenAlexW2003105295

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.