ArticleFEBS open bio2013
Role of Sulf1A in Wnt1- and Wnt6-induced growth regulation and myoblast hyper-elongation.
Article in FEBS open bio, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
8 citing papers in PubMed.
- Expression and Function of WNT6: From Development to Disease.Frontiers in cell and developmental biology · 2020Review
- Fibroblast growth factor 9 (FGF9) inhibits myogenic differentiation of C2C12 and human muscle cells.Cell cycle (Georgetown, Tex.) · 2019Article
- Non-canonical WNT6/WNT10A signal factor expression in EBV+ post-transplant smooth muscle tumors.Clinical sarcoma research · 2018Article
- Wnt6 influences the viability of mouse embryonic palatal mesenchymal cells via the β-catenin pathway.Experimental and therapeutic medicine · 2017Article
- SULF1/SULF2 reactivation during liver damage and tumour growth.Histochemistry and cell biology · 2016Article
- Expression of Sulf1 and Sulf2 in cartilage, bone and endochondral fracture healing.Histochemistry and cell biology · 2016Article
- Secreted Frizzled-Related Protein 3 (SFRP3) Is Required for Tumorigenesis of PAX3-FOXO1-Positive Alveolar Rhabdomyosarcoma.Clinical cancer research : an official journal of the American Association for Cancer Research · 2015Article
- Sulf1 has ligand-dependent effects on canonical and non-canonical Wnt signalling.Journal of cell science · 2015Article
Corrections and comments
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Sulf1A expression, which is a characteristic of embryonic muscle, is undetectable in mature muscle fibres and quiescent satellite cells, but is re-activated in vivo upon injury and in vitro following activation of satellite cells. Sulf1A is known to enhance canonical Wnt signalling, and its association with Wnt1-induced satellite cell proliferation in vitro in the present study further confirmed this. However, exogenous Wnt6 decreased satellite cell proliferation but promoted the adoption of a hyper-elongated cell morphology in myoblasts on isolated single fibres in culture. Such Wnt6-induced cellular hyper-elongation and inhibition of proliferation was found to be dependent upon Sulf1A, as treatment with Sulf1A neutralising antibodies abolished both these effects. This indicates that Sulf1A can regulate Wnt6 signalling and cellular differentiation in skeletal muscle.
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Registered trials
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