Evidence map›Paper›PMID 23772366›Full record

ArticleFEBS open bio2012

Resolvin E1 maintains macrophage function under cigarette smoke-induced oxidative stress.

Rina Takamiya, Koichi Fukunaga, Makoto Arita, Jun Miyata, Hiroyuki Seki, Naoto Minematsu, Makoto Suematsu, Koichiro Asano

Open access · goldAbstract read
In one paragraph

Article in FEBS open bio, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed
0.9field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 37 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Article
  5. Article
  6. Article
  7. Review
  8. Review
  9. Review
  10. Roles of Resolvins in Chronic Inflammatory Response.International journal of molecular sciences · 2022
    Review
  11. Review
  12. Article
  13. Review
  14. Article
  15. Article
  16. Omega 3 Fatty Acid and Skin Diseases.Frontiers in immunology · 2020
    Review
  17. Review
  18. Article
  19. Proresolving Lipid Mediators: Endogenous Modulators of Oxidative Stress.Oxidative medicine and cellular longevity · 2019
    Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Rina TakamiyaDepartment of Biochemistry, School of Medicine, Keio University, Japan ; Division of Pulmonary Medicine, Department of Medicine, School of Medicine, Keio University, Japan ; Systems Glycobiology Research Group, Advanced Science Institute, RIKEN, Japan.
Koichi Fukunaga
Makoto Arita
Jun Miyata
Hiroyuki Seki
Naoto Minematsu
Makoto Suematsu
Koichiro Asano
Keio University · JPTokai University · JPUniversity of Tokyo Health Sciences · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cigarette smoke (CS) induces oxidative stress, which disables macrophage function. In this study, we examined whether Resolvin E1 (RvE1), a pro-resolving mediator known to enhance macrophage functions, attenuates the damage of macrophages by CS extract (CSE) induced oxidative stress. RvE1 blocked p47phox translocation to plasma membrane induced by CSE in a macrophage cell line, RAW264.7 cells, resulting in suppression of superoxide production. Furthermore, pretreatment of RAW264.7 cells with RvE1 restored the phagocytic activity and reduced cell death induced by treatment of CSE. These results suggest that RvE1 plays important roles in preserving macrophage function under CS-induced oxidative stress.

Indexed as

Cigarette smokeCOPD, chronic obstructive pulmonary diseaseCS, cigarette smokeCSE, cigarette smoke extractMacrophageNOX2, NADPH oxidase2Reactive oxygen speciesResolvin E1ROS, reactive oxygen speciesRvE1, Resolvin E1

Identifiers

PMID23772366
PMCPMC3678121
OpenAlexW2038672958

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.