ArticleBrain sciences2013
Sleep patterns and homeostatic mechanisms in adolescent mice.
Article in Brain sciences, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 48 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
48 citing papers in PubMed, 80 citations in OpenAlex.
- Article
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- Sleep and circadian rhythm activity alterations during adolescence in a mouse model of neonatal fentanyl withdrawal syndrome.Neuroscience · 2025Article
- Sleep Fragmentation in TcMAC21 Mouse Model of Down Syndrome.Nature and science of sleep · 2025Article
- Developing forebrain synapses are uniquely vulnerable to sleep loss.Proceedings of the National Academy of Sciences of the United States of America · 2024Article
- Cortical parvalbumin neurons are responsible for homeostatic sleep rebound through CaMKII activation.Nature communications · 2024Article
- Long-lasting effects of disturbing the circadian rhythm or sleep in adolescence.Brain research bulletin · 2024Review
- SlumberNet: deep learning classification of sleep stages using residual neural networks.Scientific reports · 2024Article
- Loss of sleep when it is needed most - Consequences of persistent developmental sleep disruption: A scoping review of rodent models.Neurobiology of sleep and circadian rhythms · 2023Article
- Ultrastructural effects of sleep and wake on the parallel fiber synapses of the cerebellum.eLife · 2022Article
- Shank3 influences mammalian sleep development.Journal of neuroscience research · 2022Article
- Early life sleep disruption potentiates lasting sex-specific changes in behavior in genetically vulnerable Shank3 heterozygous autism model mice.Molecular autism · 2022Article
- Article
- Sleep timing and the circadian clock in mammals: Past, present and the road ahead.Seminars in cell & developmental biology · 2022Review
- Sleep's role in the development and resolution of adolescent depression.Nature reviews psychology · 2022Review
- Use of Actigraphy for a Rat Behavioural Sleep Study.Clocks & sleep · 2021Article
- Prediction of Locomotor Activity by Infrared Motion Detector on Sleep-wake State in Mice.Clinical psychopharmacology and neuroscience : the official scientific journal of the Korean College of Neuropsychopharmacology · 2021Article
- The Ontogenesis of Mammalian Sleep: Form and Function.Current sleep medicine reports · 2020Article
- Sleeping Sickness Disrupts the Sleep-Regulating Adenosine System.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2020Article
- Sleep and diurnal rest-activity rhythm disturbances in a mouse model of Alzheimer's disease.Sleep · 2020Article
Corrections and comments
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Authors and funding
5 authors at 1 institution in 1 country.
Funding
Abstract
Sleep changes were studied in mice (n = 59) from early adolescence to adulthood (postnatal days P19-111). REM sleep declined steeply in early adolescence, while total sleep remained constant and NREM sleep increased slightly. Four hours of sleep deprivation starting at light onset were performed from ages P26 through adulthood (>P60). Following this acute sleep deprivation all mice slept longer and with more consolidated sleep bouts, while NREM slow wave activity (SWA) showed high interindividual variability in the younger groups, and increased consistently only after P42. Three parameters together explained up to 67% of the variance in SWA rebound in frontal cortex, including weight-adjusted age and increase in alpha power during sleep deprivation, both of which positively correlated with the SWA response. The third, and strongest predictor was the SWA decline during the light phase in baseline: mice with high peak SWA at light onset, resulting in a large SWA decline, were more likely to show no SWA rebound after sleep deprivation, a result that was also confirmed in parietal cortex. During baseline, however, SWA showed the same homeostatic changes in adolescents and adults, declining in the course of sleep and increasing across periods of spontaneous wake. Thus, we hypothesize that, in young adolescent mice, a ceiling effect and not the immaturity of the cellular mechanisms underlying sleep homeostasis may prevent the SWA rebound when wake is extended beyond its physiological duration.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.