ArticleThe Plant cell2013
Formation of a functional maize centromere after loss of centromeric sequences and gain of ectopic sequences.
Article in The Plant cell, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.
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Who cites it
27 citing papers in PubMed, 47 citations in OpenAlex.
- Stable minichromosome and functional neocentromere derived from rye 7R chromosome arm.BMC plant biology · 2024Article
- Centromeres: From chromosome biology to biotechnology applications and synthetic genomes in plants.Plant biotechnology journal · 2022Review
- Sequence of the supernumerary B chromosome of maize provides insight into its drive mechanism and evolution.Proceedings of the National Academy of Sciences of the United States of America · 2021Article
- Chromosomal variations of Lycoris species revealed by FISH with rDNAs and centromeric histone H3 variant associated DNAs.PloS one · 2021Article
- The Genomics of Plant Satellite DNA.Progress in molecular and subcellular biology · 2021Review
- Rapid Birth or Death of Centromeres on Fragmented Chromosomes in Maize.The Plant cell · 2020Article
- Centromere deletion ineLife · 2020Article
- Back-spliced RNA from retrotransposon binds to centromere and regulates centromeric chromatin loops in maize.PLoS biology · 2020Article
- Review
- Barbara McClintock's Unsolved Chromosomal Mysteries: Parallels to Common Rearrangements and Karyotype Evolution.The Plant cell · 2018Article
- Meiotic Studies on Combinations of Chromosomes With Different Sized Centromeres in Maize.Frontiers in plant science · 2018Article
- Review
- Recurrent establishment of de novo centromeres in the pericentromeric region of maize chromosome 3.Chromosome research : an international journal on the molecular, supramolecular and evolutionary aspects of chromosome biology · 2017Article
- Satellite DNA: An Evolving Topic.Genes · 2017Review
- Isolation and characterization of centromeric repetitive DNA sequences in Saccharum spontaneum.Scientific reports · 2017Article
- Repeat Composition of CenH3-chromatin and H3K9me2-marked heterochromatin in Sugar Beet (Beta vulgaris).BMC plant biology · 2016Article
- De Novo Centromere Formation and Centromeric Sequence Expansion in Wheat and its Wide Hybrids.PLoS genetics · 2016Article
- Generation of a Maize B Centromere Minimal Map Containing the Central Core Domain.G3 (Bethesda, Md.) · 2015Article
- Stable Patterns of CENH3 Occupancy Through Maize Lineages Containing Genetically Similar Centromeres.Genetics · 2015Article
- Recombination, Pairing, and Synapsis of Homologs during Meiosis.Cold Spring Harbor perspectives in biology · 2015Review
Corrections and comments
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Authors and funding
12 authors at 4 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The maize (Zea mays) B centromere is composed of B centromere-specific repeats (ZmBs), centromere-specific satellite repeats (CentC), and centromeric retrotransposons of maize (CRM). Here we describe a newly formed B centromere in maize, which has lost CentC sequences and has dramatically reduced CRM and ZmBs sequences, but still retains the molecular features of functional centromeres, such as CENH3, H2A phosphorylation at Thr-133, H3 phosphorylation at Ser-10, and Thr-3 immunostaining signals. This new centromere is stable and can be transmitted to offspring through meiosis. Anti-CENH3 chromatin immunoprecipitation sequencing revealed that a 723-kb region from the short arm of chromosome 9 (9S) was involved in the formation of the new centromere. The 723-kb region, which is gene poor and enriched for transposons, contains two abundant DNA motifs. Genes in the new centromere region are still transcribed. The original 723-kb region showed a higher DNA methylation level compared with native centromeres but was not significantly changed when it was involved in new centromere formation. Our results indicate that functional centromeres may be formed without the known centromere-specific sequences, yet the maintenance of a high DNA methylation level seems to be crucial for the proper function of a new centromere.
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