ReviewCellular and molecular life sciences : CMLS2013
Establishment of left-right asymmetry in vertebrate development: the node in mouse embryos.
Review in Cellular and molecular life sciences : CMLS, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
21 citing papers in PubMed, 45 citations in OpenAlex.
- Novel compound heterozygous mutation inMolecular medicine reports · 2025Article
- Asymmetries of Left and Right Adrenal Glands in Neural Innervation and Glucocorticoids Production.International journal of molecular sciences · 2023Article
- Knockdown of Ift88 in fibroblasts causes extracellular matrix remodeling and decreases conduction velocity in cardiomyocyte monolayers.Frontiers in physiology · 2022Article
- Clinical diagnosis of presumed SOX2 gonadosomatic mosaicism.Ophthalmic genetics · 2021Article
- Mouse gastrulation: Coordination of tissue patterning, specification and diversification of cell fate.Mechanisms of development · 2020Review
- Long-Pentraxin 3 Affects Primary Cilium in Zebrafish Embryo and Cancer Cells via the FGF System.Cancers · 2020Article
- Review
- Phylogenetic evidence for independent origins of GDF1 and GDF3 genes in anurans and mammals.Scientific reports · 2018Article
- The Role of Hedgehog Signalling in the Formation of the Ventricular Septum.Journal of developmental biology · 2017Review
- Genetic specification of left-right asymmetry in the diaphragm muscles and their motor innervation.eLife · 2017Article
- From cytoskeletal dynamics to organ asymmetry: a nonlinear, regulative pathway underlies left-right patterning.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2016Review
- Copy-number variant analysis of classic heterotaxy highlights the importance of body patterning pathways.Human genetics · 2016Article
- Left-Right Axis Differentiation and Functional Lateralization: a Haplotype in the Methyltransferase Encoding Gene SETDB2 Might Mediate Handedness in Healthy Adults.Molecular neurobiology · 2016Article
- Left-right axis asymmetry determining human Cryptic gene is transcriptionally repressed by Snail.BMC developmental biology · 2016Article
- Extracellular matrix motion and early morphogenesis.Development (Cambridge, England) · 2016Review
- Plasticity underlies tumor progression: role of Nodal signaling.Cancer metastasis reviews · 2016Article
- Article
- Essential roles of epithelial bone morphogenetic protein signaling during prostatic development.Endocrinology · 2014Article
- Primary cilia in stem cells and neural progenitors are regulated by neutral sphingomyelinase 2 and ceramide.Molecular biology of the cell · 2014Article
- Developmental signaling: does it bridge the gap between cilia dysfunction and renal cystogenesis?Birth defects research. Part C, Embryo today : reviews · 2014Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
Abstract
Establishment of vertebrate left-right asymmetry is a critical process for normal embryonic development. After the discovery of genes expressed asymmetrically along the left-right axis in chick embryos in the mid 1990s, the molecular mechanisms responsible for left-right patterning in vertebrate embryos have been studied extensively. In this review article, we discuss the mechanisms by which the initial symmetry along the left-right axis is broken in the mouse embryo. We focus on the role of primary cilia and molecular mechanisms of ciliogenesis at the node when symmetry is broken and left-right asymmetry is established. The node is considered a signaling center for early mouse embryonic development, and the results we review here have led to a better understanding of how the node functions and establishes left-right asymmetry.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.