ArticleAnnals of biomedical engineering2013
Effect of mechanical strain on solute diffusion in human TMJ discs: an electrical conductivity study.
Article in Annals of biomedical engineering, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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Who cites it
14 citing papers in PubMed.
- Preclinical perspectives on disorders of the temporomandibular joint: Tracing the past, navigating the present, and shaping the future.The journal of pain · 2025Review
- Different effects of abnormal mechanical stress on temporomandibular joint cartilage, subchondral bone, and discs.Frontiers in physiology · 2025Review
- Critical signaling molecules in the temporomandibular joint osteoarthritis under different magnitudes of mechanical stimulation.Frontiers in pharmacology · 2024Review
- Effects of glucose concentration and oxygen partial pressure on the respiratory metabolism of sheep temporomandibular joint disc cells.Experimental and therapeutic medicine · 2023Article
- Temporomandibular Joint Condyle-Disc Morphometric Sexual Dimorphisms Independent of Skull Scaling.Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons · 2019Article
- Effect of Sustained Joint Loading on TMJ Disc Nutrient Environment.Journal of dental research · 2019Article
- Effect of Measurement Technique on TMJ Mandibular Condyle and Articular Disc Morphometry: CBCT, MRI, and Physical Measurements.Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons · 2019Article
- Mechanobehavior and Ontogenesis of the Temporomandibular Joint.Journal of dental research · 2018Review
- Electrical Conductivity Method to Determine Sexual Dimorphisms in Human Temporomandibular Disc Fixed Charge Density.Annals of biomedical engineering · 2018Article
- Jaw closing movement and sex differences in temporomandibular joint energy densities.Journal of oral rehabilitation · 2018Article
- A pilot study of nocturnal temporalis muscle activity in TMD diagnostic groups of women.Journal of oral rehabilitation · 2017Article
- Mechanobehavioral Scores in Women with and without TMJ Disc Displacement.Journal of dental research · 2017Article
- Tensile biomechanical properties of human temporomandibular joint disc: Effects of direction, region and sex.Journal of biomechanics · 2016Article
- The effects of oxygen level and glucose concentration on the metabolism of porcine TMJ disc cells.Osteoarthritis and cartilage · 2015Article
Corrections and comments
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Authors and funding
6 authors.
Funding
Abstract
This study investigated the effect of mechanical strain on solute diffusion in human TMJ discs (mean cadaver age 77.8) using the electrical conductivity method. The electrical conductivity, as well as small ion diffusivity, of male and female TMJ discs was determined under three compressive strains. In the male group, the average disc electrical conductivity (mean ± SD) at 0% strain was 5.14 ± 0.97 mS/cm, decreased to 4.50 ± 0.91 mS/cm (-12.3%) at 10% strain, and 3.93 ± 0.81 mS/cm (-23.5%) at 20% compressive strain. Correspondingly, the average disc relative ion diffusivity at 0% strain was 0.44 ± 0.08, decreased to 0.40 ± 0.08 (-8.9%) at 10% strain, and 0.36 ± 0.08 (-16.7%) at 20% compressive strain. In the female group, the average disc electrical conductivity at 0% strain was 5.84 ± 0.59 mS/cm, decreased to 5.01 ± 0.50 mS/cm (-14.2%) at 10% strain, and 4.33 ± 0.46 mS/cm (-25.8%) at 20% compressive strain. Correspondingly, the average disc relative ion diffusivity at 0% strain was 0.49 ± 0.05, decreased to 0.43 ± 0.04 (-11.3%) at 10% strain, and 0.39 ± 0.04 (-19.9%) at 20% compressive strain. The results indicated that mechanical strain significantly impeded solute diffusion through the disc. This mechanical strain effect was larger in the female than in the male human TMJ disc. This study may provide new insights into TMJ pathophysiology.
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