ArticleDiabetologia2013
Survival in dialysis patients is different between patients with diabetes as primary renal disease and patients with diabetes as a co-morbid condition.
Article in Diabetologia, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
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Who cites it
18 citing papers in PubMed.
- The long-term dialysis due to diabetic nephropathy may be associated with in-hospital death in patients with acute myocardial infarction.Heart and vessels · 2026Article
- Kidney Biopsy-Proven Diabetic and Non-Diabetic Kidney Diseases and Outcomes in Patients With Type 2 Diabetes Receiving Dialysis: The REIN Registry.Kidney medicine · 2025Article
- High-Volume Hemodiafiltration and Cool Hemodialysis Have a Beneficial Effect on Intradialytic Hemodynamics: A Randomized Cross-Over Trial of Four Intermittent Dialysis Strategies.Kidney international reports · 2022Article
- Diabetic kidney disease versus non-diabetic kidney disease in type 2 diabetic patients on dialysis: An observational cohort.Endocrinology, diabetes & metabolism · 2022Observational
- Propensity-matched comparison of mortality between peritoneal dialysis and hemodialysis in patients with type 2 diabetes.International urology and nephrology · 2022Observational
- Naoxintong capsule delay the progression of diabetic kidney disease: A real-world cohort study.Frontiers in endocrinology · 2022Article
- The risk of consequent nephropathy following initial weight loss in diabetic patients treated with sodium glucose cotransporter 2 inhibitors.Cardiovascular diabetology · 2021Observational
- Kidney Biopsy in Type 2 Diabetic Patients: Critical Reflections on Present Indications and Diagnostic Alternatives.International journal of molecular sciences · 2021Review
- Global Epidemiology, Health Outcomes, and Treatment Options for Patients With Type 2 Diabetes and Kidney Failure.Frontiers in clinical diabetes and healthcare · 2021Review
- Mortality after amputation in dialysis patients is high but not modified by diabetes status.Clinical kidney journal · 2020Article
- Low-Protein Diets in Diabetic Chronic Kidney Disease (CKD) Patients: Are They Feasible and Worth the Effort?Nutrients · 2016Observational
- Observational
- Patient characteristics and outcomes by GN subtype in ESRD.Clinical journal of the American Society of Nephrology : CJASN · 2015Observational
- Incidence of renal replacement therapy for diabetic nephropathy in the Netherlands: Dutch diabetes estimates (DUDE)-3.BMJ open · 2015Observational
- Diabetes and end-stage renal disease; a review article on new concepts.Journal of renal injury prevention · 2015Review
- Article
- From sugar to kidney: A never-ending battle.Journal of diabetes investigation · 2014Article
- Diabetic Kidney Disease: A Syndrome Rather Than a Single Disease.The review of diabetic studies : RDSReview
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Authors and funding
14 authors.
Funding
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Abstract
aims/hypothesisA previous study in Dutch dialysis patients showed no survival difference between patients with diabetes as primary renal disease and those with diabetes as a co-morbid condition. As this was not in line with our hypothesis, we aimed to verify these results in a larger international cohort of dialysis patients.
methodsFor the present prospective study, we used data from the European Renal Association-European Dialysis and Transplant Association (ERA-EDTA) Registry. Incident dialysis patients with data on co-morbidities (n = 15,419) were monitored until kidney transplantation, death or end of the study period (5 years). Cox regression was performed to compare survival for patients with diabetes as primary renal disease, patients with diabetes as a co-morbid condition and non-diabetic patients.
resultsOf the study population, 3,624 patients (24%) had diabetes as primary renal disease and 1,193 (11%) had diabetes as a co-morbid condition whereas the majority had no diabetes (n = 10,602). During follow-up, 7,584 (49%) patients died. In both groups of diabetic patients mortality was higher compared with the non-diabetic patients. Mortality was higher in patients with diabetes as primary renal disease than in patients with diabetes as a co-morbid condition, adjusted for age, sex, country and malignancy (HR 1.20, 95% CI 1.10, 1.30). An analysis stratified by dialysis modality yielded similar results. CONCLUSIONS/
interpretationOverall mortality was significantly higher in patients with diabetes as primary renal disease compared with those with diabetes as a co-morbid condition. This suggests that survival in diabetic dialysis patients is affected by the extent to which diabetes has induced organ damage.
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