ArticleApplied and environmental microbiology2013
Adherence to and invasion of human intestinal cells by Arcobacter species and their virulence genotypes.
Article in Applied and environmental microbiology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 45 papers, 1 of them a synthesis that pooled it.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
45 citing papers in PubMed, 1 synthesis or guideline pooled it.
- The Immunopathogenic Potential of Arcobacter butzleri - Lessons from a Meta-Analysis of Murine Infection Studies.PloS one · 2016Pooled it
- Determinants of Entero-Invasive and Non-Entero-Invasive Diarrheagenic Bacteria Among HIV-Positive and HIV-Negative Adults in Ghana.Medical sciences (Basel, Switzerland) · 2025Observational
- Pathogenicity of Arcobacter cryaerophilus in two human intestinal cell lines.Gut pathogens · 2025Article
- Isolation and Virulence Gene Profiling of Arcobacter spp. from Seafood and Its Environment.Current microbiology · 2025Article
- Investigation and characterization of Aliarcobacter spp. isolated from cattle slaughterhouse in Türkiye.International microbiology : the official journal of the Spanish Society for Microbiology · 2024Article
- Pathogenicity assessment of Arcobacter butzleri isolated from Canadian agricultural surface water.BMC microbiology · 2024Article
- Virulence genotype and phenotype of two clinical isolates of Arcobacter butzleri obtained from patients with different pathologies.Archives of microbiology · 2023Article
- Marine Bacterioplankton Community Dynamics and Potentially Pathogenic Bacteria in Seawater around Jeju Island, South Korea, via Metabarcoding.International journal of molecular sciences · 2023Article
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- Microbial mat compositions and localization patterns explain the virulence of black band disease in corals.NPJ biofilms and microbiomes · 2023Article
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- The Prevalence ofMicroorganisms · 2022Review
- CRISPR Contributes to Adhesion, Invasion, and Biofilm Formation in Streptococcus agalactiae by Repressing Capsular Polysaccharide Production.Microbiology spectrum · 2022Article
- CAMPYAIR, a New Selective, Differential Medium forMicroorganisms · 2022Article
- Article
- CRISPR-dependent endogenous gene regulation is required for virulence in piscineEmerging microbes & infections · 2021Article
- Characterization of Arcobacter spp. Isolated from human diarrheal, non-diarrheal and food samples in Thailand.PloS one · 2021Article
- Antimicrobial Susceptibility and Genomic Analysis ofFrontiers in cellular and infection microbiology · 2021Article
- The incidence and antimicrobial resistance ofIranian journal of microbiology · 2020Article
- Rumen epithelial transcriptome and microbiome profiles of rumen epithelium and contents of beef cattle with and without liver abscesses.Journal of animal science · 2020Article
Corrections and comments
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The genus Arcobacter is composed of 17 species which have been isolated from various sources. Of particular interest are A. butzleri, A. cryaerophilus, and A. skirrowii, as these have been associated with human cases of diarrhea, the probable transmission routes being through the ingestion of contaminated drinking water and food. To date, only limited studies of virulence traits in this genus have been undertaken. The present study used 60 Arcobacter strains isolated from different sources, representing 16 of the 17 species of the genus, to investigate their ability to adhere to and invade the human intestinal cell line Caco-2. In addition, the presence of five putative virulence genes (ciaB, cadF, cj1349, hecA, and irgA) was screened for in these strains by PCR. All Arcobacter species except A. bivalviorum and Arcobacter sp. strain W63 adhered to Caco-2 cells, and most species (10/16) were invasive. The most invasive species were A. skirrowii, A. cryaerophilus, A. butzleri, and A. defluvii. All invasive strains were positive for ciaB (encoding a putative invasion protein). Other putative virulence genes were present in other species, i.e., A. butzleri (cadF, cj1349, irgA, and hecA), A. trophiarum (cj1349), A. ellisii (cj1349), and A. defluvii (irgA). No virulence genes were detected in strains which showed little or no invasion of Caco-2 cells. These results indicate that many Arcobacter species are potential pathogens of humans and animals.
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