ReviewCurrent opinion in chemical biology2013
Synthetic fluorescent probes for monovalent copper.
Review in Current opinion in chemical biology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 41 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
41 citing papers in PubMed.
- Simultaneous Imaging of CuAngewandte Chemie (International ed. in English) · 2026Article
- Molecular Design Strategies Enabling Activity-Based Sensing and Labeling as a Platform for Probing Enzyme Activity, Redox Regulation, and Transition-Metal Signaling.Bioconjugate chemistry · 2026Review
- A histochemical approach to activity-based copper sensing reveals cuproplasia-dependent vulnerabilities in cancer.Proceedings of the National Academy of Sciences of the United States of America · 2025Article
- An Activity-Based Sensing Approach to Multiplex Mapping of Labile Copper Pools by Stimulated Raman Scattering.Journal of the American Chemical Society · 2024Article
- Synthesis of 2MP-CuNPs Fluorescent Probes and Their Application in Tetracycline Detection.Sensors (Basel, Switzerland) · 2024Article
- Metalloallostery and Transition Metal Signaling: Bioinorganic Copper Chemistry Beyond Active Sites.Angewandte Chemie (International ed. in English) · 2023Review
- Investigations of cellular copper metabolism in ovarian cancer cells using a ratiometric fluorescent copper dye.Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry · 2023Article
- Protein metalation in a nutshell.FEBS letters · 2023Review
- Advances in reaction-based synthetic fluorescent probes for studying the role of zinc and copper ions in living systems.Journal of clinical biochemistry and nutrition · 2023Article
- Oxidation state-specific fluorescent copper sensors reveal oncogene-driven redox changes that regulate labile copper(II) pools.Proceedings of the National Academy of Sciences of the United States of America · 2022Article
- Protein metalation in biology.Current opinion in chemical biology · 2022Review
- A Chemical Tool for Guiding Li Therapy.ACS central science · 2021Article
- Selective Detection of CuAngewandte Chemie (International ed. in English) · 2021Article
- Copper Toxicity Is Not Just Oxidative Damage: Zinc Systems and Insight from Wilson Disease.Biomedicines · 2021Review
- Retromer retrieves the Wilson disease protein ATP7B from endolysosomes in a copper-dependent manner.Journal of cell science · 2020Article
- Recent endeavors on molecular imaging for mapping metals in biology.Biophysics reports · 2020Article
- Using Ligand-Accelerated Catalysis to Repurpose Fluorogenic Reactions for Platinum or Copper.ACS central science · 2020Article
- Activity-Based Sensing with a Metal-Directed Acyl Imidazole Strategy Reveals Cell Type-Dependent Pools of Labile Brain Copper.Journal of the American Chemical Society · 2020Article
- Activity-Based Sensing: A Synthetic Methods Approach for Selective Molecular Imaging and Beyond.Angewandte Chemie (International ed. in English) · 2020Review
- Metal-Dependent DNAzymes for the Quantitative Detection of Metal Ions in Living Cells: Recent Progress, Current Challenges, and Latest Results on FRET Ratiometric Sensors.Inorganic chemistry · 2019Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author.
Funding
Abstract
Fluorescent probes are powerful and cost-effective tools for the detection of metal ions in biological systems. Compared to non-redox-active metal ions, the design of fluorescent probes for biological copper is challenging. Within the reducing cellular environment, copper is predominantly present in its monovalent oxidation state; therefore, the design of fluorescent probes for biological copper must take into account the rich redox and coordination chemistry of Cu(I). Recent progress in understanding the underlying solution chemistry and photophysical pathways led to the development of new probes that offer high fluorescence contrast and excellent selectivity towards monovalent copper.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.